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Chloride Channel Chloride Channel

Cat.No.  Name Information
M7041 NPPB NPPB is a inhibits calcium-sensitive chloride currents.
M14207 Chlorotoxin TFA Chlorotoxin TFA is a peptide isolated from the venom of the scorpion Leiurus quinquestriatus, acts as a chloride channel blocker. Anti-cancer activity.
M11196 R(+)-IAA-94 R(+)-IAA-94 (R(+)-Methylindazone) is an effective chloride channel blocker. R(+)-IAA-94 inhibits Nef-sdAb19 interaction and binds to Nef.
M10200 Chlorotoxin Chlorotoxin is a 36 amino-acid peptide with anticancer activity, it is also a chloride channel blocker.
M9159 Adjudin Adjudin (also known as AF-2364) is a potent Cl- channel blocker, with a superior mitochondria-inhibitory effect.
M8680 Ani9 Ani9 is a potent and highly selective anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A) inhibitor that completely inhibited ANO1 chloride current with submicromolar potency.
M7346 T16Ainh -A01 T16Ainh - A01 is a Ca2+-activated Cl- channel transmembrane protein 16A (TMEM16A) inhibitor.
M6695 Eact Eact is a activator of Ca 2+-activated Cl - channel transmembrane protein 16A (TMEM16A).
M6554 CaCCinh-A01 CaCCinh-A01 is a calcium-activated chloride channel (CaCC) inhibitor.
M4633 Atractyloside Atractyloside potassium salt is a toxic diterpenoid glycoside, which can be isolated from the fruit of Atractyloside. Atractyloside potassium salt is a highly effective and specific inhibitor of mitochondrial ADP/ATP transport. Atractyloside potassium salt inhibited the chloride channel in rat heart mitochondrial membrane.
M54869 NMD670 NMD670 is a first-in-class small molecule inhibitor of the skeletal muscle specific chloride ion channel (ClC-1). NMD670 improves skeletal muscle function in rat models with myasthenia gravis.
M54413 GaTx2 GaTx2 is a seletive and a high affinity inhibitor of ClC-2 channels with a voltage-dependent apparent KD of ∼20 pM.
M39021 Anthracene-9-carboxylic acid Anthracene-9-carboxylic acid (9-Anthracenecarboxylic acid) is an anthracene derivative traditionally used to block and identify Ca2+-activated Cl- currents (CaCCs) in various cell types, like diverse smooth muscle cells, epithelial cells and salivary gland cells.
M28826 T16A(inh)-C01  T16A(inh)-C01 is an inhibitor of TMEM16A (ANO1). T16A(inh)-C01 blocks chloride channel mediated by ANO1 with an IC50 of 8.4 μM, without interfering with calcium signaling.
M14209 Picrotoxinin Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABAA receptor antagonist, which negatively modulates the action of GABA on GABAA receptors.
M14208 Endovion Endovion (NS3728) is a pharmacological anion channel inhibitor (like chloride channel) and the specific VRAC/VSOAC blocker. Endovion (NS3728) is also an Anoctamin-1 (ANO 1) channel inhibitor.




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