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-IAA-94.gif)
R(+)-IAA-94 (R(+)-Methylindazone) is an effective chloride channel blocker. R(+)-IAA-94 inhibits Nef-sdAb19 interaction and binds to Nef.
| Molecular Weight | 357.23 |
| Formula | C17H18Cl2O4 |
| CAS Number | 54197-31-8 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Chloride Channel Products |
|---|
| NS1652
NS1652 is a reversible anion conductance inhibitor, blocks chloride channel, with an IC50 of 1.6 μM in human and mouse red blood cells. |
| NMD670
NMD670 is a first-in-class small molecule inhibitor of the skeletal muscle specific chloride ion channel (ClC-1). NMD670 improves skeletal muscle function in rat models with myasthenia gravis. |
| GaTx2
GaTx2 is a seletive and a high affinity inhibitor of ClC-2 channels with a voltage-dependent apparent KD of ∼20 pM. |
| Anthracene-9-carboxylic acid
Anthracene-9-carboxylic acid (9-Anthracenecarboxylic acid) is an anthracene derivative traditionally used to block and identify Ca2+-activated Cl- currents (CaCCs) in various cell types, like diverse smooth muscle cells, epithelial cells and salivary gland cells. |
| T16A(inh)-C01
T16A(inh)-C01 is an inhibitor of TMEM16A (ANO1). T16A(inh)-C01 blocks chloride channel mediated by ANO1 with an IC50 of 8.4 μM, without interfering with calcium signaling. |
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