Catalog

Antifolate Antifolate

Inhibitors

Cat.No.	Name	Information
M7108	Pemetrexed	Pemetrexed is a thymidylate synthetase inhibitor, also inhibits dihydrofolate reductase, GARFT and AICART.
M5866	Pemetrexed Disodium Hydrate	Pemetrexed Disodium Hydrate is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.
M3303	Pralatrexate	Pralatrexate is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines.
M3090	Trimethoprim	Trimethoprim is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.
M2711	Folinic acid calcium salt	Folinic acid is an adjuvant used in cancer chemotherapy involving the compound methotrexate.
M2228	Abitrexate (Methotrexate)	Abitrexate is an antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities.