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The results of the current study demonstrate that the HRPE cells express the reduced-folate transporter that mediates the cellular uptake of N5 methyltetrahydrofolate, the predominant form of folate in blood.
| Cell Experiment | |
|---|---|
| Cell lines | HRPE cells |
| Preparation method | One milliliter of a hypotonic medium (10 mM Tris-HCl buffer, pH 8) containing 1 μM unlabeled N5-methyltetrahydrofolate was added to each well, and die cells were lysed by freezing and thawing. |
| Concentrations | 1 μM |
| Incubation time | 2 h |
| Animal Experiment | |
|---|---|
| Animal models | |
| Formulation | |
| Dosages | |
| Administration | |
| Molecular Weight | 497.52 |
| Formula | C20H23CaN7O6 |
| CAS Number | 26560-38-3 |
| Solubility (25°C) | 10 mM in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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