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Pemetrexed disodium heptahydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.
| Molecular Weight | 599.5 |
| Formula | C20H21N5O6.7H2O.2Na |
| CAS Number | 357166-29-1 |
| Form | Solid |
| Solubility (25°C) | Water 100 mg/mL (ultrasonic) |
| Storage | 4°C, dry, sealed |
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