About 11 results found for searched term "Tenofovir" (0.055 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4958 | Tenofovir alafenamide | HIV Protease |
| GS-7340 | ||
| Tenofovir alafenamide (GS-7340) is an investigational oral proagent of tenofovir (TFV) that more efficiently delivers TFV into lymphoid cells and tissues than TFV disoproxil fumarate. | ||
| M5051 | Tenofovir | Reverse Transcriptase |
| GS 1278; PMPA; TDF | ||
| Tenofovir is a nucleotide reverse transcriptase inhibitor used in studies related to HIV and chronic hepatitis B (HBV). | ||
| M5052 | Tenofovir Disoproxil Fumarate | HIV Protease |
| Tenofovir DF | ||
| Tenofovir Disoproxil Fumarate belongs to a class of antiretroviral compounds, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination. | ||
| M6274 | Tenofovir Disoproxil | HIV Protease |
| Bis(POC)-PMPA; GS 4331 | ||
| Tenofovir dsoproxil is a nucleotide reverse transcriptase inhibitor. | ||
| M10364 | Tenofovir hydrate | HIV Protease |
| GS 1278 hydrate; PMPA hydrate | ||
| Tenofovir hydrate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. | ||
| M20783 | Tenofovir alafenamide hemifumarate | Reverse Transcriptase |
| TAF hemifumarate, GS-7340 hemifumarate | ||
| Tenofovir alafenamide (TAF, GS-7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection. | ||
| M20784 | Tenofovir alafenamide fumarate | Reverse Transcriptase |
| TAF fumarate, GS-7340 fumarate | ||
| Tenofovir alafenamide (TAF, GS-7340) fumarate is a precursor compound of Tenofovir and a novel nucleotide reverse transcriptase inhibitor for use in studies related to HIV-1 infection. | ||
| M30871 | Tenofovir exalidex | HIV Protease |
| CMX-157 | ||
| Tenofovir exalidex (CMX157) is a lipid conjugate of the acyclic nucleotide analog Tenofovir with activity against both wild-type and antiretroviral drug-resistant HIV strains, including multidrug nucleoside/nucleotide analog-resistant viruses. Tenofovir exalidex is active against all major subtypes of HIV-1 and HIV-2 in fresh human PBMCs and against all HIV-1 strains evaluated in monocyte-derived macrophages, with EC50s ranging between 0.2 and 7.2 nM. CMX157 is orally available and has no apparent toxicity. Tenofovir exalidex also shows antiviral activity against HBV. | ||
| M55842 | Tenofovir diphosphate | Reverse Transcriptase |
| Tenofovir diphosphate (TFV-DP) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT). | ||
| M55841 | Tenofovir diphosphate triethylamine | Reverse Transcriptase |
| Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT). | ||
| M55818 | Tenofovir diphosphate disodium | Anti-infection |
| Tenofovir diphosphate disodium is an antiretroviral agent and an inhibitor of DNA polymerases. | ||
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