About 16 results found for searched term "Remodelin" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3797 | Remodelin | Histone Acetyltransferase |
| Remodelin is a novel, potent Acetyl-transferase NAT 10 inhibitor that mediates nuclear shape rescue in laminopathic (LMNA-depleted) cells via microtubule reorganization. | ||
| M9410 | Remodelin hydrobromide | Histone Acetyltransferase |
| Remodelin HBr | ||
| Remodelin hydrobromide is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10. | ||
| M4206 | Icariside-I | Others |
| Icariside I (Icarisid I) is a metabolite of Icarlin, which regulates bone remodeling and can be used in the study of osteoporosis. | ||
| M4286 | Angoroside-C | Others |
| Angoroside C is a phenylalanine extracted from Radix Scrophulariae, which is beneficial for ventricular remodeling. | ||
| M8874 | C188-9 | STAT |
| TTI-101 | ||
| C188-9 is a small-molecule STAT3 inhibitor, can block Th2 and Th17 cell expansion and cytokine production to prevent house dust mite (HDM)-induced airway inflammation and remodeling. | ||
| M11464 | Recombinant Human RANKL (E.coli) | Cytokines and Growth Factors |
| CD254 | ||
| Recombinant Human RANKL is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL is the ligand of nuclear factor (NF)-κB (RANK). | ||
| M28109 | PF-3758309 hydrochloride | PAK |
| PF-03758309 hydrochloride | ||
| PF-3758309 (PF-03758309) hydrochloride is a potent, orally available, and reversible ATP-competitive inhibitor of PAK4 (Kd= 2.7 nM; Ki=18.7 nM). PF-3758309 hydrochloride has the expected cellular functions of a PAK4 inhibitor: inhibition of anchorage-independent growth, induction of apoptosis, cytoskeletal remodeling, and inhibition of proliferation. | ||
| M29452 | TH5427 | Others |
| TH5427 is a promising, targeted inhibitor that can be used to further study NUDT5 activity and ADP-ribose metabolism. TH5427, blocks progestin-dependent, PAR-derived nuclear ATP synthesis and subsequent chromatin remodeling, gene regulation and proliferation in breast cancer cells. NUDT5 is recently identified as a rheostat of hormone-dependent gene regulation and proliferation in breast cancer cells. | ||
| M29453 | TH5427 hydrochloride | DNA/RNA Synthesis |
| TH5427 hydrochloride is a potent, selective NUDT5 inhibitor (IC50=29 nM). TH5427 hydrochloride shows an apparent 690-fold selectivity for NUDT5 over MTH1. TH5427 hydrochloride blocks progestin-dependent, PAR-derived nuclear ATP synthesis and subsequent chromatin remodeling, gene regulation and proliferation in breast cancer cells. | ||
| M29763 | Myoseverin | Microtubule |
| Myoseverina, a microtubule-binding molecule, induces the reversible fission of multinucleated myotubes into mononucleated fragments. Myoseverina affects the expression of a variety of growth factor, immunomodulatory, extracellular matrix-remodeling, and stress response genes, consistent with the activation of pathways involved in wound healing and tissue regeneration. | ||
| M30017 | Zaprinast | PDE |
| M&B 22948 | ||
| Zaprinast (M&B 22948) is an inhibitor of cGMP-selective Phosphodiesterases(PDEs). Zaprinast is a G protein-coupled receptor (GPR) 35 agonist which activates rat GPR35 strongly and activates human GPR35 moderately. Zaprinast reduces vessel remodeling through antiproliferative and proapoptotic effects. | ||
| M31007 | PF-3758309 dihydrochloride | PAK |
| PF-03758309 dihydrochloride | ||
| PF-3758309 (PF-03758309) dihydrochloride is a potent, orally available, and reversible ATP-competitive inhibitor of PAK4 (Kd= 2.7 nM; Ki=18.7 nM). PF-3758309 dihydrochloride has the expected cellular functions of a PAK4 inhibitor: inhibition of anchorage-independent growth, induction of apoptosis, cytoskeletal remodeling, and inhibition of proliferation. | ||
| M40717 | UNC0321 | Histone Methyltransferase |
| UNC0321 is a high affinity inhibitor of GPCRs and can be used in studies related to chromatin remodeling. It is also a selective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and an IC50 value of 6-9 nM.In addition, UNC0321 also inhibits GLP with an IC50 value of 15-23 nM. | ||
| M40861 | Ganglioside GM1 | Others |
| Ganglioside is a glycoside analog derived from animal brain tissue that promotes neural remodeling, such as neuronal cell survival, axonal growth and synaptogenesis. It also has a protective effect against secondary neurodegeneration after injury. | ||
| M43969 | Recombinant Mouse MMP-12 (HEK293, C-6His) | Enzymes & Regulators |
| Matrix metalloproteinase-12 | ||
| Matrix metalloproteinase-12 (MMP12) contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. | ||
| M55375 | Recombinant Human CD143/ACE (E. coli, N-GST) | Cytokines and Growth Factors |
| Dipeptidyl carboxypeptidase I; DCP1 | ||
| CD143/ACE Protein is a recombinant human Angiotensin I-converting enzyme (ACE, CD143) which hydrolyzes small peptides such as angiotensin I, bradykinin, substance P, LH-RH and several others and thus plays a key role in blood pressure regulation and vascular remodeling. ACE plays a crucial role in blood pressure regulation, vascular remodeling, and immunity. | ||
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