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 About 16 results found for searched term "Remodelin" (0.125 seconds)

Cat.No.  Name Target
M3797 Remodelin Histone Acetyltransferase
Remodelin is a novel, potent Acetyl-transferase NAT 10 inhibitor that mediates nuclear shape rescue in laminopathic (LMNA-depleted) cells via microtubule reorganization.
M9410 Remodelin hydrobromide Histone Acetyltransferase
Remodelin HBr
Remodelin hydrobromide is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.
M4206 Icariside-I Others
Icariside I (Icarisid I) is a metabolite of Icarlin, which regulates bone remodeling and can be used in the study of osteoporosis.
M4286 Angoroside-C Others
Angoroside C is a phenylalanine extracted from Radix Scrophulariae, which is beneficial for ventricular remodeling.
M8874 C188-9 STAT
TTI-101
C188-9 is a small-molecule STAT3 inhibitor, can block Th2 and Th17 cell expansion and cytokine production to prevent house dust mite (HDM)-induced airway inflammation and remodeling.
M11464 Recombinant Human RANKL (E.coli) Recombinant Proteins
CD254
Recombinant Human RANKL is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL is the ligand of nuclear factor (NF)-κB (RANK).
M20641 XRK3F2 Others
XRK3F2 is an inhibitor of the p62-ZZ domain that blunts MM-induced Runx2 suppression in vitro, and induces new bone formation and remodeling in the presence of tumor in vivo.
M28109 PF-3758309 hydrochloride PAK
PF-03758309 hydrochloride
PF-3758309 (PF-03758309) hydrochloride is a potent, orally available, and reversible ATP-competitive inhibitor of PAK4 (Kd= 2.7 nM; Ki=18.7 nM). PF-3758309 hydrochloride has the expected cellular functions of a PAK4 inhibitor: inhibition of anchorage-independent growth, induction of apoptosis, cytoskeletal remodeling, and inhibition of proliferation.
M29452 TH5427  Others
TH5427 is a promising, targeted inhibitor that can be used to further study NUDT5 activity and ADP-ribose metabolism. TH5427, blocks progestin-dependent, PAR-derived nuclear ATP synthesis and subsequent chromatin remodeling, gene regulation and proliferation in breast cancer cells. NUDT5 is recently identified as a rheostat of hormone-dependent gene regulation and proliferation in breast cancer cells.
M29453 TH5427 hydrochloride  DNA/RNA Synthesis
TH5427 hydrochloride is a potent, selective NUDT5 inhibitor (IC50=29 nM). TH5427 hydrochloride shows an apparent 690-fold selectivity for NUDT5 over MTH1. TH5427 hydrochloride blocks progestin-dependent, PAR-derived nuclear ATP synthesis and subsequent chromatin remodeling, gene regulation and proliferation in breast cancer cells.
M29763 Myoseverin  Microtubule
Myoseverina, a microtubule-binding molecule, induces the reversible fission of multinucleated myotubes into mononucleated fragments. Myoseverina affects the expression of a variety of growth factor, immunomodulatory, extracellular matrix-remodeling, and stress response genes, consistent with the activation of pathways involved in wound healing and tissue regeneration.
M30017 Zaprinast PDE
M&B 22948
Zaprinast (M&B 22948) is an inhibitor of cGMP-selective Phosphodiesterases(PDEs). Zaprinast is a G protein-coupled receptor (GPR) 35 agonist which activates rat GPR35 strongly and activates human GPR35 moderately. Zaprinast reduces vessel remodeling through antiproliferative and proapoptotic effects.
M31007 PF-3758309 dihydrochloride PAK
PF-03758309 dihydrochloride
PF-3758309 (PF-03758309) dihydrochloride is a potent, orally available, and reversible ATP-competitive inhibitor of PAK4 (Kd= 2.7 nM; Ki=18.7 nM). PF-3758309 dihydrochloride has the expected cellular functions of a PAK4 inhibitor: inhibition of anchorage-independent growth, induction of apoptosis, cytoskeletal remodeling, and inhibition of proliferation.
M40717 UNC0321 Histone Methyltransferase
UNC0321 is a high affinity inhibitor of GPCRs and can be used in studies related to chromatin remodeling. It is also a selective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and an IC50 value of 6-9 nM.In addition, UNC0321 also inhibits GLP with an IC50 value of 15-23 nM.
M40861 Ganglioside GM1 Others
Ganglioside is a glycoside analog derived from animal brain tissue that promotes neural remodeling, such as neuronal cell survival, axonal growth and synaptogenesis. It also has a protective effect against secondary neurodegeneration after injury.
M43969 Recombinant Mouse MMP-12 (Mammalian, C-6His) Recombinant Proteins
Matrix metalloproteinase-12
Matrix metalloproteinase-12 (MMP12) contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity.



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