About 11 results found for searched term "RAD51" (0.135 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2978 | RI-1 | RAD51 |
| RAD51 inhibitor 1 | ||
| RI-1 is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM. | ||
| M5277 | B02 | DNA/RNA Synthesis |
| B-02 | ||
| B02 is a small-molecule inhibitor of human RAD51 with an IC50 of 27.4 μM, but does not inhibit its E. coli homologue RecA (IC50 > 250 μM). | ||
| M6148 | RS-1 | CRISPR/Cas9 |
| RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51. It is an HDR(homology-directed repair) enhancer. | ||
| M13725 | IBR2 | RAD51 |
| IBR2 is a potent and specific RAD51 inhibitor and inhibits RAD51-mediated DNA double-strand break repair. | ||
| M20065 | WAY-298516 | Androgen Receptor |
| WAY-298516 is a modulating rad51 | ||
| M21625 | CAM833 | RAD51 |
| CAM833 is a potent orthosteric inhibitor of the interaction between BRCA2 and RAD51 with a Kd of 366 nM against the ChimRAD51 protein. CAM833 also inhibits RAD51 oligomerization. | ||
| M21649 | Bractoppin | DNA/RNA Synthesis |
| Bractoppin is a potent and selective inhibitor of phosphopeptide recognition by the human BRCA1 tandem(t) BRCT domain with IC50 of 74 nM. Bractoppin diminishes BRCA1 recruitment to DNA breaks, in turn suppressing damage-induced G2 arrest and assembly of the recombinase, RAD51. | ||
| M27723 | Amuvatinib hydrochloride | c-Kit |
| MP470 hydrochloride; HPK 56 hydrochloride | ||
| Amuvatinib hydrochloride (MP470 hydrochloride) is an orally bioavailable multi-targeted tyrosine kinase inhibitor with potent activity against mutant c-Kit, PDGFRα, Flt3, c-Met and c-Ret. Amuvatinib hydrochloride (MP470 hydrochloride) is also a DNA repair suppressor through suppression of DNA repair protein RAD51, thereby disrupting DNA damage repair. Antineoplastic activity. | ||
| M29325 | BODIPY 581/591 C11 | Fluorescent Dye |
| BODIPY 581/591 C11 is a BODIPY borofluoroprene derivative with good light stability and low fluorescence artifacts. BODIPY 581/591 C11 can be used for study lipid peroxidation and antioxidant properties in living cells, or detect ferroptosis by reaction with hydroxyl radicals. BODIPY 581/591 C11 is emitted at 591 nm (reduced prototype), or redshifted to 510 nm (oxidized type). The excitation wavelengths were 581 nm (reduced prototype) and 500 nm (oxidized type). | ||
| M30247 | DIDS | RAD51 |
| DIDS is a potent RAD51 inhibitor. DIDS inhibits the RAD51-mediated homologous pairing and strand-exchange reactions. DIDS inhibits anion exchange and binding to the red blood cell membrane. | ||
| M43429 | PROTAC α-synuclein degrader 5 | PROTAC |
| PROTAC α-synuclein degrader 5 is a highly selective small-molecule degraders (PROTAC) of α-synuclein aggregates, with an DC50 of 7.51 μM and the highest degradation rate Dmax of 89%. | ||
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