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DIDS is a potent RAD51 inhibitor. DIDS inhibits the RAD51-mediated homologous pairing and strand-exchange reactions. DIDS inhibits anion exchange and binding to the red blood cell membrane.
| Molecular Weight | 454.52 |
| Formula | C16H10N2O6S4 |
| CAS Number | 53005-05-3 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[1] Denis Velic, et al. Molecules. Molecular Determinant of DIDS Analogs Targeting RAD51 Activity
| Related RAD51 Products |
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| RAD51-IN-3
RAD51-IN-3 is a Rad51 inhibitor. |
| CAM833
CAM833 is a potent orthosteric inhibitor of the interaction between BRCA2 and RAD51 with a Kd of 366 nM against the ChimRAD51 protein. CAM833 also inhibits RAD51 oligomerization. |
| IBR2
IBR2 is a potent and specific RAD51 inhibitor and inhibits RAD51-mediated DNA double-strand break repair. |
| RI-1
RI-1 is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM. |
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