All AbMole products are for research use only, cannot be used for human consumption.
CAM833 is a potent orthosteric inhibitor of the interaction between BRCA2 and RAD51 with a Kd of 366 nM against the ChimRAD51 protein. CAM833 also inhibits RAD51 oligomerization. CAM833 increases the progression of G2/M-arrested cells into apoptosis.
| Molecular Weight | 528.96 |
| Formula | C26H26ClFN4O5 |
| CAS Number | 2758364-02-0 |
| Solubility (25°C) | DMSO ≥ 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related RAD51 Products |
|---|
| RAD51-IN-3
RAD51-IN-3 is a Rad51 inhibitor. |
| DIDS
DIDS is a potent RAD51 inhibitor. DIDS inhibits the RAD51-mediated homologous pairing and strand-exchange reactions. DIDS inhibits anion exchange and binding to the red blood cell membrane. |
| IBR2
IBR2 is a potent and specific RAD51 inhibitor and inhibits RAD51-mediated DNA double-strand break repair. |
| RI-1
RI-1 is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM. |
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Products are for research use only. Not for human use. We do not sell to patients.
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