About 31 results found for searched term "Phospholipase C" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M50304 | Phospholipase C | Enzymes & Coenzymes |
| Phospholipase C (PLCs) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||
| M2176 | Dexamethasone | GCR |
| Prednisolone F; Hexadecadrol | ||
| Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist that induces the production of phospholipase A2 inhibitory protein.It can be used to construct models of allergic conjunctivitis. | ||
| M2626 | Dexamethasone Sodium Phosphate | Animal Modeling |
| Dexamethasone phosphate disodium | ||
| Dexamethasone Sodium Phosphate is a glucocorticoid receptor agonist that induces the production of lipocortin, a phospholipase A2 inhibitory protein. Dexamethasone inhibits autophagy levels in damaged cells in a dose-dependent manner. It can be used to construct models of allergic conjunctivitis. | ||
| M5170 | U73122 | Phospholipase |
| U-73122 | ||
| U73122 is a potent inhibitor of phospholipase C, phospholipase A2 and 5-LO (5-lipoxygenase). | ||
| M5855 | Rilapladib | Phospholipase |
| SB 659032 | ||
| Rilapladib (SB 659032) is a selective Lp-PLA2 (lipoprotein-associated phospholipase A2) inhibitor with an IC50 of 230 pM. Rilapladib (SB 659032) is also a PAFR (Platelet Activating Factor Receptor) antagonist. | ||
| M6979 | ML348 | Phospholipase |
| GNF-Pf-1127; ML-348 | ||
| ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor with an IC50 of 210 nM. | ||
| M7894 | LY311727 | Others |
| LY311727 is an oral active compound; Phospholipase A2 (sPLA2; Group activity highlights) inhibitors. | ||
| M7922 | MJ33 lithium salt | Phospholipase |
| MJ33-OH lithium | ||
| MJ33-OH lithium is a metabolite of MJ33. MJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6. | ||
| M8168 | sPLA2 inhibitor | Phospholipase |
| Secretory phospholipase A2 inhibitor blocks the activation of NF-κB, Akt, p38 MAPK and ERK pathways. | ||
| M8731 | ASB14780 | Others |
| ASB14780 is an indole-based selective and potent cytosolic phospholipase A2α inhibitor (IC50 = 20 nM/cPLA2α and >10 μM/sPLA2α). | ||
| M14508 | 3-Nitrocoumarin | Phospholipase |
| 3-Nitrocoumarin (3-NC) is a potent and selective Phospholipase C-γ (PLC-γ) inhibitor. | ||
| M14509 | CAY10650 | Phospholipase |
| CAY10650 is a highly potent cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 value of 12 nM. CAY10650 suppresses lipid droplets formation and PGE2 secretion. | ||
| M14510 | D609 | Phospholipase |
| D609 is a selective competitive inhibitor of phosphatidyl choline-specific phospholipase C (PC-PLC), with Ki of 6.4 μM. | ||
| M14511 | LEI-401 | Phospholipase |
| LEI-401 is a first-in-class, selective, and CNS-active NAPE-PLD (N-acylphosphatidylethanolamine phospholipase D) inhibitor, with an IC50 of 27 nM. | ||
| M14514 | N-(p-amylcinnamoyl) Anthranilic Acid | Phospholipase |
| ACA | ||
| N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker. | ||
| M20582 | ST 271 | Phospholipase |
| ST271 is a tyrphostin-like protein tyrosine kinase (PTK) inhibitor which inhibits phospholipase D (PLD) activity. | ||
| M21681 | Compound 48/80 trihydrochloride | Phospholipase |
| C48/80 trihydrochloride | ||
| Compound 48/80 trihydrochloride is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways. | ||
| M27746 | FKGK11 | Phospholipase |
| FKGK11 is a potent and selective inhibitor of GVIA iPLA2 (Group VIA calcium-independent phospholipase A2). FKGK11 can be used for the research of ovarian cancer and neurological disorders such as peripheral nerve injury and multiple sclerosis. | ||
| M28097 | BAPTA tetrasodium | Phospholipase |
| BAPTA | ||
| BAPTA tetrasodium is a selective chelator for calcium. BAPTA tetrasodium, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrasodium is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA tetrasodium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators. | ||
| M28382 | Lp-PLA2-IN-1 | Phospholipase |
| Lp-PLA2-IN-1 is a potent Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2-IN-1 has the potential for atherosclerosis, Alzheimer's disease research. | ||
| M28836 | Varespladib sodium | Phospholipase |
| LY315920 sodium | ||
| Varespladib sodium (LY315920 sodium) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib sodium exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively. | ||
| M29064 | LYPLAL1-IN-1 | Others |
| LYPLAL1-IN-1 (Compound 11) is an selective covalent small-molecule inhibitor of Lysophospholipase-like 1 (LYPLAL1) with an IC50 of 0.006 μM. LYPLAL1-IN-1 increases glucose production. | ||
| M29337 | ARN19874 | Phospholipase |
| ARN19874 is a selective, reversible uncompetitive N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) activity inhibitor with an IC50 of ~34 μM. | ||
| M30557 | BAPTA tetrapotassium | Phospholipase |
| BAPTA | ||
| BAPTA tetrapotassium is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrapotassium is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA tetrapotassium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators. | ||
| M30798 | Bromoenol lactone | Phospholipase |
| (6E)-Bromoenol lactone | ||
| Bromoenol lactone ((6E)-Bromoenol lactone) is a suicide-based irreversible, selective, potent inhibitor of calcium-independent phospholipase A2 (iPLA2β) with an IC50 value of approximately 7 μM, which inhibits antigen-stimulated mast cell exocytosis without blocking Ca2+ influx. | ||
| M39167 | Uralsaponin D | Phosphatase |
| Uralsaponin D is a saponin that can be isolated from Glycyrrhiza inflata. Uralsaponin D inhibits phospholipase A2 (PLA2) with an IC50 value of 32.2 μM. | ||
| M39174 | Rhamnetin | Phospholipase |
| Rhamnetin is a quercetin derivative found in Coriandrum sativum, inhibits secretory phospholipase A2, with antioxidant and anti-inflammatory activity. | ||
| M42570 | Lp-PLA2-IN-15 | Phospholipase |
| Lp-PLA2-IN-15 is a lipoprotein-associated phospholipase A2 (Lp-PLA 2) inhibitor, which can be used in the research of Alzheimer's disease, etc. | ||
| M42571 | Lp-PLA2-IN-16 | Phospholipase |
| Lp-PLA2-IN-16 is a lipoprotein-associated phospholipase A2 (Lp-PLA 2) inhibitor, which can be used in the research of Alzheimer's disease, etc. | ||
| M42581 | CGP-35949 sodium | Phospholipase |
| CGP-35949 sodium is a LTD4 antagonist with phospholipase inhibitory activity. | ||
| M45137 | Fuzapladib | Integrin |
| IS-741 | ||
| Fuzapladib is a leukocyte adhesion molecule and an orally active inhibitor of leukocyte function-associated antigen type 1 (LFA-1) activation.Fuzapladib is also a phospholipase A2 (PLA2) inhibitor, which exerts anti-inflammatory activity by inhibiting the migration of leukocytes to sites of inflammation. | ||
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