All AbMole products are for research use only, cannot be used for human consumption.
Rilapladib (SB 659032) is a selective Lp-PLA2 (lipoprotein-associated phospholipase A2) inhibitor with an IC50 of 230 pM. Rilapladib (SB 659032) is also a PAFR (Platelet Activating Factor Receptor) antagonist.
| Cell Experiment | |
|---|---|
| Cell lines | Platelet-rich plasma samples |
| Preparation method | Lp-PLA2 activity was measured in parallel using plasma samples that were derived from PRP that had been treated either with vehicle or rilapladib (100 nM) for 5 minutes using [3H]-PAF as the substrate as previously described. |
| Concentrations | 100 nM |
| Incubation time | 5 minutes |
| Animal Experiment | |
|---|---|
| Animal models | |
| Formulation | |
| Dosages | |
| Administration | |
| Molecular Weight | 735.8 |
| Formula | C40H38F5N3O3S |
| CAS Number | 412950-08-4 |
| Solubility (25°C) | DMSO 78 mg/mL |
| Storage | Powder -20°C |
| Related Phospholipase Products |
|---|
| ML-298
ML298 is a potent and selective inhibitor of Phospholipase D2 (PLD2) with an IC50 of 355 nM. |
| LCL521
LCL521 is an acid ceramidase (ACDase) inhibitor. |
| SPK-601
SPK-601 (LMV-601) is an inhibitor of the phosphatidylcholine-specific phospholipase C (PC-PLC). |
| CCT129957
CCT129957 is an indole derivative and a potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of ~3 μM and a GC50 of 15 μM. |
| ONO-RS-082
ONO-RS-082 is an inhibitor of phospholipase A (PLA). |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
