All AbMole products are for research use only, cannot be used for human consumption.
ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM). ML348 exhibits 14-fold selectivity for LYPLA1 over LYPLA2. ML348 is also selective over a panel of ~30 other serine hydrolases.
| Molecular Weight | 415.79 |
| Formula | C18H17ClF3N3O3 |
| CAS Number | 899713-86-1 |
| Solubility (25°C) | DMSO 15 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Phospholipase Products |
|---|
| ML-298
ML298 is a potent and selective inhibitor of Phospholipase D2 (PLD2) with an IC50 of 355 nM. |
| LCL521
LCL521 is an acid ceramidase (ACDase) inhibitor. |
| SPK-601
SPK-601 (LMV-601) is an inhibitor of the phosphatidylcholine-specific phospholipase C (PC-PLC). |
| CCT129957
CCT129957 is an indole derivative and a potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of ~3 μM and a GC50 of 15 μM. |
| ONO-RS-082
ONO-RS-082 is an inhibitor of phospholipase A (PLA). |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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