About 34 results found for searched term "Phospholipase A2" (0.116 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M58156 | Recombinant Human PRDX6 Protein (E. coli, N-6His) | Cytokines and Growth Factors |
| Peroxiredoxin-6; 1-Cys Peroxiredoxin; Acidic Calcium-Independent Phospholipase A2 | ||
| Peroxiredoxin 6 (PRDX6) belongs to the thiol-specific antioxidant protein family, it is involved in redox regulation of the cell and can reduce Hydrogen peroxide and short chain organic, fatty acid, and phospholipid hydroperoxides. Peroxiredoxin 6 may regulates phospholipid turnover and protectes against oxidative injury. | ||
| M49416 | Recombinant Human PLA2G2A Protein (HEK293, C-His) | Cytokines and Growth Factors |
| Phospholipase A2 group IIA | ||
| PLA2G2A, is a peripheral membrane protein that belongs to the phospholipase A2 family. PLA2G2A plays a role in anti-bacterial defense, inflammation and eicosanoid generation, in clearance of apoptotic cells, and in the Wnt signaling pathway. | ||
| M49417 | Recombinant Mouse PLA2G2A Protein (Yeast, C-His) | Cytokines and Growth Factors |
| Phospholipase A2 group IIA | ||
| PLA2G2A, is a peripheral membrane protein that belongs to the phospholipase A2 family. PLA2G2A plays a role in anti-bacterial defense, inflammation and eicosanoid generation, in clearance of apoptotic cells, and in the Wnt signaling pathway. | ||
| M52550 | Phospholipase A2 | Phospholipase |
| Phospholipase A2 (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid (AA). | ||
| M2176 | Dexamethasone | GCR |
| Prednisolone F; Hexadecadrol | ||
| Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist that induces the production of phospholipase A2 inhibitory protein.It can be used to construct models of allergic conjunctivitis. | ||
| M2528 | Clofazimine | Anti-infection |
| Clofazimine is a rhimophenazine dye, originally developed for the treatment of tuberculosis, it has both antimicrobial and antiinflammatory activity, postulated mechanisms of action include intercalation of clofazimine with bacterial DNA and increasing levels of cellular phospholipase A2. | ||
| M2626 | Dexamethasone Sodium Phosphate | Animal Modeling |
| Dexamethasone phosphate disodium | ||
| Dexamethasone Sodium Phosphate is a glucocorticoid receptor agonist that induces the production of lipocortin, a phospholipase A2 inhibitory protein. Dexamethasone inhibits autophagy levels in damaged cells in a dose-dependent manner. It can be used to construct models of allergic conjunctivitis. | ||
| M5170 | U73122 | Phospholipase |
| U-73122 | ||
| U73122 is a potent inhibitor of phospholipase C, phospholipase A2 and 5-LO (5-lipoxygenase). | ||
| M5855 | Rilapladib | Phospholipase |
| SB 659032 | ||
| Rilapladib (SB 659032) is a selective Lp-PLA2 (lipoprotein-associated phospholipase A2) inhibitor with an IC50 of 230 pM. Rilapladib (SB 659032) is also a PAFR (Platelet Activating Factor Receptor) antagonist. | ||
| M6979 | ML348 | Phospholipase |
| GNF-Pf-1127; ML-348 | ||
| ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor with an IC50 of 210 nM. | ||
| M6980 | ML 349 | Others |
| ML 349 is a selective and reversible lysophospholipase 2 (LYPLA2) inhibitor. | ||
| M7076 | OBAA | Others |
| OBAA is a phospholipase A 2 inhibitor. | ||
| M7894 | LY311727 | Others |
| LY311727 is an oral active compound; Phospholipase A2 (sPLA2; Group activity highlights) inhibitors. | ||
| M7922 | MJ33 lithium salt | Phospholipase |
| MJ33-OH lithium | ||
| MJ33-OH lithium is a metabolite of MJ33. MJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6. | ||
| M8168 | sPLA2 inhibitor | Phospholipase |
| Secretory phospholipase A2 inhibitor blocks the activation of NF-κB, Akt, p38 MAPK and ERK pathways. | ||
| M8478 | YM-26734 | Others |
| YM-26734 is a competitive inhibitor of the secreted (Group II) form of phospholipase A2. | ||
| M8731 | ASB14780 | Others |
| ASB14780 is an indole-based selective and potent cytosolic phospholipase A2α inhibitor (IC50 = 20 nM/cPLA2α and >10 μM/sPLA2α). | ||
| M14509 | CAY10650 | Phospholipase |
| CAY10650 is a highly potent cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 value of 12 nM. CAY10650 suppresses lipid droplets formation and PGE2 secretion. | ||
| M14511 | LEI-401 | Phospholipase |
| LEI-401 is a first-in-class, selective, and CNS-active NAPE-PLD (N-acylphosphatidylethanolamine phospholipase D) inhibitor, with an IC50 of 27 nM. | ||
| M14514 | N-(p-amylcinnamoyl) Anthranilic Acid | Phospholipase |
| ACA | ||
| N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker. | ||
| M14515 | Varespladib methyl | Phospholipase |
| A-002; LY333013 | ||
| Varespladib methyl (A-002; LY333013) is a selective inhibitor of group II secretory phospholipase A2 (PLA2). | ||
| M27746 | FKGK11 | Phospholipase |
| FKGK11 is a potent and selective inhibitor of GVIA iPLA2 (Group VIA calcium-independent phospholipase A2). FKGK11 can be used for the research of ovarian cancer and neurological disorders such as peripheral nerve injury and multiple sclerosis. | ||
| M28097 | BAPTA tetrasodium | Phospholipase |
| BAPTA | ||
| BAPTA tetrasodium is a selective chelator for calcium. BAPTA tetrasodium, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrasodium is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA tetrasodium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators. | ||
| M28382 | Lp-PLA2-IN-1 | Phospholipase |
| Lp-PLA2-IN-1 is a potent Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2-IN-1 has the potential for atherosclerosis, Alzheimer's disease research. | ||
| M28835 | Me-Indoxam | Phospholipase |
| Me-Indoxam is a potent and cell-impermeable secreted phospholipase A2 (sPLA2) inhibitor. | ||
| M28836 | Varespladib sodium | Phospholipase |
| LY315920 sodium | ||
| Varespladib sodium (LY315920 sodium) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib sodium exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively. | ||
| M30557 | BAPTA tetrapotassium | Phospholipase |
| BAPTA | ||
| BAPTA tetrapotassium is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrapotassium is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA tetrapotassium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators. | ||
| M30798 | Bromoenol lactone | Phospholipase |
| (6E)-Bromoenol lactone | ||
| Bromoenol lactone ((6E)-Bromoenol lactone) is a suicide-based irreversible, selective, potent inhibitor of calcium-independent phospholipase A2 (iPLA2β) with an IC50 value of approximately 7 μM, which inhibits antigen-stimulated mast cell exocytosis without blocking Ca2+ influx. | ||
| M39167 | Uralsaponin D | Phosphatase |
| Uralsaponin D is a saponin that can be isolated from Glycyrrhiza inflata. Uralsaponin D inhibits phospholipase A2 (PLA2) with an IC50 value of 32.2 μM. | ||
| M39174 | Rhamnetin | Phospholipase |
| Rhamnetin is a quercetin derivative found in Coriandrum sativum, inhibits secretory phospholipase A2, with antioxidant and anti-inflammatory activity. | ||
| M42570 | Lp-PLA2-IN-15 | Phospholipase |
| Lp-PLA2-IN-15 is a lipoprotein-associated phospholipase A2 (Lp-PLA 2) inhibitor, which can be used in the research of Alzheimer's disease, etc. | ||
| M42571 | Lp-PLA2-IN-16 | Phospholipase |
| Lp-PLA2-IN-16 is a lipoprotein-associated phospholipase A2 (Lp-PLA 2) inhibitor, which can be used in the research of Alzheimer's disease, etc. | ||
| M45028 | trans-4-phenylbut-3-en-2-one | Phospholipase |
| trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). | ||
| M45137 | Fuzapladib | Integrin |
| IS-741 | ||
| Fuzapladib is a leukocyte adhesion molecule and an orally active inhibitor of leukocyte function-associated antigen type 1 (LFA-1) activation.Fuzapladib is also a phospholipase A2 (PLA2) inhibitor, which exerts anti-inflammatory activity by inhibiting the migration of leukocytes to sites of inflammation. | ||
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