About 27 results found for searched term "PP2" (0.052 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1981 | Torkinib (PP242) | mTOR |
| Torkinib | ||
| Torkinib (PP242) is a selective, ATP-competitive mTORC1/mTORC2 inhibitor with IC50 of 8 nM. | ||
| M2011 | PP121 | VEGFR/PDGFR |
| PP121 is a dual inhibitor of tyrosine and phosphoinositide kinases. | ||
| M2331 | PP2 | Src-bcr-Abl |
| AG 1879; AGL1879 | ||
| PP2 (AGL 1879) is a selective inhibitor of Src-family tyrosine kinases with >10,000-fold selectivity over ZAP-70 and JAK2. | ||
| M3147 | PPQ-102 | CFTR |
| CFTR Inhibitor | ||
| PPQ-102 is a potent CFTR inhibitor which can completely inhibited CFTR chloride current with IC 50 approximately 90 nM. | ||
| M3976 | (20S)-Protopanaxadiol | P-glycoprotein |
| 20(S)-APPD; 20-Epiprotopanaxadiol | ||
| (20S)-Protopanaxadiol (aPPD) is one of the aglycones of the ginsenosides and has a wide range of pharmacological activities. | ||
| M4082 | Protopanaxtriol | Others |
| 20(R)-APPT; 20(R)-Protopanaxatriol | ||
| 20(R)-Protopanaxatriol is a natural ginsenoside ligand of Re, Rf, Rg1, Rg2 and Rh. | ||
| M8755 | DIM-C-pPhCO2Me | Others |
| DIM-C-pPhCO2Me is a NR4A1 (Nur77) antagonist that exhibit potent anticancer activity in pancreatic, colon, breast, kidney, and rhabdomyosarcoma cells. | ||
| M9001 | ML-265 (TEPP-46) | Pyruvate Kinase |
| TEPP-46; ML265 | ||
| Ml-265 (TEPP-46) is an effective activator of pyruvate kinase M2 (PKM2). | ||
| M9575 | NVP-DPP-728 dihydrochloride | Dipeptidyl Peptidase |
| NVP-728 2HCl | ||
| NVP-DPP-728 dihydrochloride is a potent and selective dipeptidyl peptidase IV inhibitor. | ||
| M10834 | Indeglitazar | Others |
| PPM 204 | ||
| Indeglitazar (PPM 204) is an orally active PPAR pan-agonist that acts on PPARα, PPARδ and PPARγ. | ||
| M13983 | Abarelix Acetate | LHRH/GnRH |
| PPI 149 Acetate; R 3827 Acetate | ||
| Abarelix Acetate (PPI 149 Acetate; R 3827 Acetate) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer research. | ||
| M25440 | Recombinant Human Osteopontin/SPP1 Protein (HEK293, C-6His) | Cytokines and Growth Factors |
| OPN; Secreted Phosphoprotein 1 | ||
| Osteopontin/SPP1 is a secreted multifunctional glycoprotein. Its putative functions include roles in bone metabolism, immune regulation, wound healing, cell survival, and tumor progression. Osteopontin/SPP1 acts as a cytokine that is involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10. | ||
| M29740 | Enpp-1-IN-12 | PDE |
| Enpp-1-IN-12 (compound 43) is a potent and orally active ecto-nucleotide pyrophosphatase/phosphodiesterases 1 (ENPP1) inhibitor, with a Ki of 41 nM. Enpp-1-IN-12 exhibits anti-tumor activity. | ||
| M30084 | PPI-2458 | Others |
| PPI-2458 is a potent, orally active, selective and irreversible inhibitor of methionine aminopeptidase-2 (MetAP-2). PPI-2458 can be used for arthritis and lymphoma research. | ||
| M41589 | PPARγ-IN-2 | PPAR |
| PPARγ-IN-2 is a PPARγ inhibitor. | ||
| M42797 | PEX5-PEX14 PPI-IN-2 | Others |
| PEX5-PEX14 PPI-IN-2 is a PEX14-PEX5 protein-protein interaction (PPI) inhibitor. | ||
| M43036 | PPO-IN-2 | Others |
| PPO-IN-2 is an inhibitor of protoporphyrinogen IX oxidase with an Ki of 16 nM. | ||
| M43295 | KRPpSQRHGSKY-NH2 | Others |
| KRPpSQRHGSKY-NH2 is a biological active peptide. | ||
| M43593 | SLU-PP-332 | Estrogen Receptor |
| SLU-PP-332 is a pan-Estrogen Receptor/ERR agonist with EC50 values of 98, 230 and 430 nM for ERRα, ERRβ and ERRγ, respectively. | ||
| M43598 | SLU-PP-1072 | Estrogen Receptor |
| SLU-PP-1072 is a dual ERRα/γ inverse agonist, used in Prostate cancer (PCa) research. | ||
| M50449 | CPP2 | Others |
| CPP2 is a cell-penetrating peptide, with a high intracellular translocation efficiency. | ||
| M50859 | CMV pp65(13-27) | Others |
| CMV pp65(13-27) is a biological active peptide. | ||
| M54061 | [cPP1-7, NPY19-23, Ala31, Aib32, Gln34]-hPancreatic Polypeptide | Neuropeptide Receptor |
| [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent and selective neuropeptide Y Y5 receptor agonist with an IC50 of 0.24 nM for binding to the hY5 receptor. | ||
| M54186 | pp60 c-src (521-533) (phosphorylated) | Others |
| pp60 c-src (521-533) (phosphorylated) is a peptide corresponding to the pp60c-src carboxy terminal regulatory domain, phosphorylated at Tyr527. | ||
| M55024 | Recombinant Human DPP4/CD26 (HEK293, C-6His) | Cytokines and Growth Factors |
| Dipeptidyl Peptidase 4; DPP IV; ADCP-2 | ||
| DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. | ||
| M55549 | Recombinant Mouse DPP-4/CD26 Protein (HEK293, N-hFc) | Cytokines and Growth Factors |
| Dipeptidyl Peptidase 4; DPP IV | ||
| Dipeptidyl peptidase-4 (DPP4, CD26) is a serine exopeptidase belonging to the S9B protein family. The enzyme is a type II transmembrane glycoprotein, expressed on the surface of many cell types. It is also present in serum and other body fluids in a truncated form (sCD26/DPPIV). | ||
| M56757 | Enpp-1-IN-2 | PDE |
| Enpp-1-IN-2 is a potent ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1) inhibitor with IC50 values of 0.26, 0.48 and 2.0 μM evaluated by means of TG-mAMP, pNP-TMP, and ATP assays, respectively. | ||
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