About 27 results found for searched term "OB3" (0.099 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2381 | AMD3465 hexahydrobromide (AMD3465 ) | CXCR |
| GENZ-644494 hexahydrobromide | ||
| AMD3465 hexahydrobromide（AMD3465 ) is an effective CXCR4 antagonist that inhibits 12G5 mAb in SupT1 cells. The IC50 values of CXCL12AF647 and CXCR4 were 0.75 nM and 18 nM, respectively. AMD 3465 also effectively inhibited X4 HIV replication (IC50, 1-10 nM), but not R5 HIV replication. | ||
| M3963 | Bruceine A | NF-κB |
| Dihydrobrusatol; NSC310616 | ||
| Brucaine A (Brucea javanica A) is a natural bitter bitter compound, extracted from the dried fruit of Brucea javanica, which can act on dog scorch. | ||
| M3626 | Cobimetinib (GDC-0973) | MEK |
| Cobimetinib ; XL518 | ||
| Cobimetinib (GDC-0973, RG7420) is an effective, selective, oral MEK1 inhibitor with an IC50 of 4.2 nM against MEK1. In addition, Cobimetinib is an inhibitor of Akt. | ||
| M3646 | Cyclobenzaprine hydrochloride | 5-HT Receptor |
| Cyclobenzaprine HCl; MK130 hydrochloride | ||
| Cyclobenzaprine hydrochloride is a skeletal muscle relaxant and a central nervous system (CNS) depressant. | ||
| M10604 | Pirtobrutinib (LOXO-305) | BTK |
| LY 3527727; RXC-005 | ||
| Pirtobrutinib (LOXO-305; LY 3527727; RXC-005) is a first-in-class, highly selective, non-covalent, next-generation BTK inhibitor with an IC50 of 5.69 nM in WT BTK HEK cells.Pirtobrutinib's selectivity for BTK more than 300 times more selective than other 370 kinases. Pirtobrutinib can be used in studies related to chronic lymphocytic leukemia (CLL). | ||
| M6804 | IBMX | PDE |
| IMX; Isobutylmethylxanthine; Methylisobutylxanthine; NSC165960; SC2964; 3-isobutyl-1-methylxanthine | ||
| IBMX is a pDE inhibitor (non-selective) with IC50 values of 6.5±1.2, 26.3±3.9 and 31.7±5.3 μM for PDE3, 4 and 5 respectively. | ||
| M10150 | Poly-D-lysine hydrobromide (30,000-70,000) | Others |
| D-Lysine homopolymer hydrobromide | ||
| Poly-D-lysine is a positively charged amino acid polymer with approximately one HBr per lysine residue. The hydrobromide allows the poly-D-lysine to be in a crystalline form soluble in water. | ||
| M10275 | Bobcat339 | DNA Methyltransferase |
| Bobcat-339 | ||
| Bobcat339 is a novel cytosine-based TET enzyme inhibitor with IC50s of 33 and 73 uM for TET1/2, it does not inhibit the DNA methyltransferase DNMT3a. | ||
| M10865 | Poly-D-lysine hydrobromide (150,000-300,000) | Cell Culture |
| Poly-D-lysine HBr | ||
| Poly-D-lysine hydrobromide (MW 150,000-300,000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. | ||
| M11332 | diABZI trihydrochloride | STING |
| Diamidobenzimidazole STING Agonist-1 3HCl | ||
| diABZI (STING agonist-1) trihydrochloride is a selective agonist of interferon gene-stimulated receptor (STING), with EC50 scores of 130 nM and 186 nM in mice and humans, respectively. | ||
| M13813 | Bobcat339 hydrochloride | DNA Methyltransferase |
| Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of TET enzyme, with the IC50s of 33 μM and 73 μM for TET1 and TET2, respectively. | ||
| M14134 | Rociletinib hydrobromide | EGFR/HER2 |
| CO-1686 hydrobromide; AVL-301 hydrobromide; CNX-419 hydrobromide | ||
| Rociletinib hydrobromide (CO-1686 hydrobromide) is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively. | ||
| M14389 | Methyl acetylacetate | Metabolite/Endogenous Metabolite |
| Acetoacetate methyl ester; Methyl 3-oxobutanoate; Methyl 3-oxobutyrate; Methyl acetoacetate; Methyl acetylacetate | ||
| Methyl acetylacetate is an endogenous metabolite. | ||
| M16588 | Pinobanksin 3-(2-methyl)butyrate | Flavonoids |
| Pinobanksin 3-(2-methyl)butyrate | ||
| M18182 | Arenobufagin 3-hemisuberate | Others |
| Arenobufagin 3-hemisuberate | ||
| M20428 | Retigabine 2HCl | Potassium Channel |
| N-(2-amino-4-[fluorobenzylamino]-phenyl) carbamic acid (2HCl); D-23129 2HCl; Ezogabine 2HCl | ||
| Retigabine is a novel anticonvulsant with activity in a broad range of seizure models. The mechanism of action involves opening of neuronal K(V)7.2-7.5 (formerly KCNQ2-5) voltage-activated K(+) channels. | ||
| M21587 | OBI-3424 | Others |
| TH-3424 | ||
| OBI-3424 is a highly selective precursor compound that can be converted into an effective dna alkylating agent by AKR1C3(aldokeone reductase 1C3). It can be used in studies of hepatocellular carcinoma, castration-resistant prostate cancer and acute lymphoblastic leukemia (ALL). | ||
| M50915 | apoB (4372-4392) | Others |
| apoB (4372-4392) is a potent lipoprotein(a) assembly inhibitor, with an IC50 of 40 μM. | ||
| M51183 | Obestatin(11-23)mouse, rat | Others |
| Obestatin(11-23)mouse, rat is a polypeptide involved in regulating energy balance and inhibiting eating. | ||
| M51500 | OB3 | Others |
| OB3, a derivative of Leptin, show more effective than leptin in reducing obesity and diabetes in mouse models. | ||
| M52842 | [D-Leu-4]-OB3 | PD-1/PD-L1 |
| [D-Leu-4]-OB3 inhibits expressions of pro-inflammatory, proliferative and metastatic genes and PD-L1 expression. | ||
| M54028 | (6S, 9S, 12S)-Benzyl 12-benzyl-9-isobutyl-2, 2-dimethyl-4, 7, 10-trioxo-6-phenethyl-3-oxa-5, 8, 11-triazatridecan-13-oate | Amino Acid Derivatives |
| (6S,9S,12S)-Benzyl 12-benzyl-9-isobutyl-2,2-dimethyl-4,7,10-trioxo-6-phenethyl-3-oxa-5,8,11-triazatridecan-13-oate is a phenylalanine derivative. | ||
| M55197 | CID1231538 | GPR/FFAR |
| CID1231538 is a potent GPR35 antagonist, with IC50 of 0.55 μM. CID1231538 is a benzothiazole analogue. | ||
| M55763 | Antimicrobial agent-33 | Antibiotic |
| Antimicrobial agent-33 is an antimicrobial agent, with MIC values of 2-64 μg/mL. | ||
| M57355 | 4-Aminobenzoic-2,3,5,6-d4 Acid Methyl Ester | Others |
| 4-Aminobenzoic-2,3,5,6-d4 Acid Methyl Ester | ||
| M58046 | 2-(4-pinacolatoboronphenyl)-3,3-diphenylacrylonitrile | Others |
| 2-(4-pinacolatoboronphenyl)-3,3-diphenylacrylonitrile | ||
| M58708 | Recombinant Human FGFR2 Protein (HEK293, C-His) | Cytokines and Growth Factors |
| Fibroblast growth factor receptor 2; CD332 | ||
| FGFR2, also known as CD332, acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. FGFR2 plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. It also promotes cell proliferation in keratinocytes and imature osteoblasts, but promotes apoptosis in differentiated osteoblasts. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
