About 23 results found for searched term "Nap-FF" (0.139 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M8491 | Nap-FF | Others |
| Nap-FF (2-Naa-FF) is a cell penetrant dipeptide that self-assembly and adopt the β-sheet structures to form prion-like nanofibrils of small molecules (PriSM). | ||
| M2753 | Hemicholinium 3 | AChR/AChE |
| Hemicholinium dibromide; HC-3 | ||
| Hemicholinium 3 is a compound which blocks the reuptake of choline by the high-affinity choline transporter (ChT) at the presynapse. Hemicholinium 3 is a competitive inhibitor of the high affinity choline transporter (HACU) with a Ki value of 25 nM. | ||
| M5424 | Asenapine maleate | 5-HT Receptor |
| Org 5222 | ||
| Asenapine maleate is a high-affinity antagonist of various receptors including serotonin receptors (5-HT), norepinephrine (NA), dopamine receptors, and histamine receptors, and can be used in studies related to neurodivergent disorders as well as depressive manic depression. | ||
| M8609 | MM-206 | Others |
| MM-206 is a cell-permeable, non-cytotoxic naphthalene sulfonamide compound effectively inhibits STAT3 DNA-binding activity (IC50 = 2. | ||
| M10028 | PAβN 2HCl | Anti-infection |
| MC-207110 dihydrochloride; Phe-Arg-β-naphthylamide dihydrochloride | ||
| Phe-Arg-β-naphthylamide 2HCl is an efflux pump inhibitor (EPI), it acts on the major multidrug resistance efflux transporters of Gram-negative bacteria. | ||
| M10148 | Juglone | Anti-infection |
| 5-Hydroxy-1,4-naphthalenedione | ||
| Juglone is a natural naphthoquinone found in the black walnut (Juglans regia) shows antimicrobial activity. The compound is unstable in solution and is recommended to be prepared and used immediately. | ||
| M10974 | 3,4-Dimethoxycinnamic acid | ROS |
| O-Methylferulic acid | ||
| 3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata. 3,4-Dimethoxycinnamic acid exerts an anti-apoptotic effect on L-02 cells through a ROS-mediated signaling pathway. | ||
| M13408 | SNAP 94847 hydrochloride | Others |
| SNAP 94847 Hydrochloride is a novel high affinity selective melanin concentration hormone receptor 1 (MCHR1) antagonist with antidepressant like activity. SNAP 94847 Hydrochloride is a high-affinity antagonist (pA2=7.81) of MYo-inositol phosphate formation induced by MCH. | ||
| M14025 | HT-2157 | Neuropeptide Receptor |
| SNAP 37889 | ||
| HT-2157 (SNAP 37889) is a selective, high-affinity, competitive antagonists of galanin-3 receptor (Gal3). | ||
| M14797 | Tanaproget | Progesterone Receptor |
| NSP-989 | ||
| Tanaproget (NSP-989) is a novel nonsteroidal progesterone receptor agonist which can bind to the PR from various species with a higher relative affinity than reference steroidal progestins. | ||
| M19381 | Guaiacin | Phosphatase |
| Guaiacin is a arylnaphthalene type lignin isolated from the barks of Machilus thunbergii SIEB. et ZUCC (Lauraceae). Guaiacin significantly increases alkaline phosphatase activity and osteoblast differentiation. | ||
| M20395 | Tetrabenazine (Xenazine) | Dopamine Receptor |
| Tetrabenazine(Nitoman, Xenazine) acts primarily as a reversible high-affinity inhibitor of mono-amine uptake into granular vesicles of presynaptic neurons by binding selectively to VMAT-2 Also blocks dopamine D2 receptors, but this affinity is 1,000-fold lower than its affinity for VMAT-2. | ||
| M21796 | Asenapine hydrochloride | 5-HT Receptor |
| Asenapine hydrochloride is a high-affinity antagonist of various receptors including serotonin receptors (5-HT), norepinephrine (NA), dopamine receptors, and histamine receptors, and is used in studies related to neurodivergent disorders, as well as depressive manic depression. | ||
| M25387 | Daclizumab | IL Receptor/Related |
| Zenapax; Ro 24-7375 | ||
| Daclizumab (Zenapax) is a humanized, monoclonal antibody that blocks CD25 (α-subunit of the high-affinity interleukin-2 receptor (IL-2R-HA)). Daclizumab (Zenapax) reversibly binds to CD25and prevents the interaction of IL-2 with the IL-2R-HA. | ||
| M28002 | Tenapanor hydrochloride | Na+/H+ Exchanger (NHE) |
| AZD1722 hydrochloride; RDX5791 hydrochloride | ||
| Tenapanor (AZD1722) hydrochloride is a first-in-class, potent, orally active sodium/hydrogen exchange isomer 3 (NHE3) inhibitor that reduces intestinal phosphate absorption primarily by decreasing passive paracellular phosphate flux. Tenapanor hydrochloride reduces intestinal absorption of phosphate by reducing passive paracellular phosphate flux. Tenapanor hydrochloride is used in studies related to chronic renal insufficiency, hyperphosphatemia, constipation, and irritable bowel syndrome. | ||
| M28605 | Pseudouridimycin | DNA/RNA Synthesis |
| PUM | ||
| Pseudouridimycin (PUM), an antibiotic, is a selective bacterial RNA polymerase (RNAP) inhibitor. Pseudouridimycin is a C-nucleoside analogue that is effective against both Gram-negative and Gram-positive bacteria. | ||
| M29387 | MS4077 | PROTAC |
| MS4077 is an anaplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 37 nM for binding affinity to ALK. | ||
| M30163 | SNAP 94847 | GPR/FFAR |
| SNAP 94847 is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCHR1) antagonist with (Ki= 2.2 nM, Kd=530 pM), it displays >80-fold and >500-fold selectivity over MCHα1A and MCHD2 receptors respectively. SNAP 94847 binds with high affinity to the mouse and rat MCHR1 with minimal cross-reactivity to other GPCR, ion channels, enzymes, and transporters. | ||
| M30665 | Nefazodone | 5-HT Receptor |
| Nefazodone is an orally active phenylpiperazine antidepressant. Nefazodone can potently and selectively block postsynaptic 5-HT2A receptors, and moderately inhibit 5-HT and noradrenaline reuptake. Nefazodone can also relieve the adverse effects of stress on the the immune system of mice. Nefazodone has a high affinity for CYP3A4 isoenzyme, which indicates that it has certain risk of agent-agent interaction. | ||
| M30816 | Chlorphenesin carbamate | Others |
| Maolate; U 19646 | ||
| Chlorphenesin carbamate is a centrally acting skeletal muscle relaxant. Chlorphenesin carbamate can be used for the research of pain and discomfort related to skeletal muscle trauma and inflammation. Chlorphenesin carbamate is a selective blocker of polysynaptic pathways at the spinal and supra-spinal levels. Antinociceptive effect. | ||
| M40861 | Ganglioside GM1 | Others |
| Ganglioside is a glycoside analog derived from animal brain tissue that promotes neural remodeling, such as neuronal cell survival, axonal growth and synaptogenesis. It also has a protective effect against secondary neurodegeneration after injury. | ||
| M42393 | VU534 | FAAH |
| VU534 is a NAPE-PLD agonist with an EC50 of 0.30 μM.In addition, VU534 can dependently enhance Efferocytosis in macrophages. VU534 can be used in studies of cardiometabolic diseases. | ||
| M45379 | Trofinetide | Peptides |
| NNZ-2566 | ||
| Trofinetide, a water-soluble analog of glycine-proline-glutamic acid (GPE), uses the unnatural amino acid 2-methylproline in place of the proline found in the natural compound, and works by enhancing synaptic activity, restoring synaptic structure, inhibiting the effects of inflammatory compounds in the brain, increasing antioxidant responses, reducing injury-induced cell death, and increasing central IGF-1 presence. It has neuroprotective activity and can be used in studies related to Rett syndrome. | ||
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