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Phe-Arg-β-naphthylamide 2HCl is an efflux pump inhibitor (EPI), it acts on the major multidrug resistance efflux transporters of Gram-negative bacteria. Phe-Arg β-naphthylamide lowers fluoroquinolone resistance in Pseudomonas aeruginosa. Phe-Arg β-naphthylamide dihydrochloride has been used to evaluate the contribution of efflux pumps to antimicrobial resistance. It has also been used for minimal inhibitory concentration testing in the presence of an efflux pump inhibitor.
| Molecular Weight | 519.47 |
| Formula | C25H32Cl2N6O2 |
| CAS Number | 100929-99-5 |
| Solubility (25°C) | DMSO 60 mg/mL Water 12 mg/mL |
| Storage | 2-8°C, dry, sealed |
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