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Asenapine hydrochloride

Cat. No. M21796

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Asenapine hydrochloride Structure

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Quality Control & Documentation
Biological Activity

Asenapine hydrochloride is a high-affinity antagonist of various receptors including serotonin receptors (5-HT), norepinephrine (NA), dopamine receptors, and histamine receptors, and is used in studies related to neurodivergent disorders, as well as depressive manic depression.

Chemical Information
Molecular Weight 322.23
Formula C17H17Cl2NO
CAS Number 1412458-61-7
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jolanta Orzelska-Grka, et al. Int J Mol Sci. New Atypical Antipsychotics in the Treatment of Schizophrenia and Depression

[2] Sabrina Meyer Krigaard, et al. J Child Adolesc Psychopharmacol. A Meta-Analysis of Antipsychotic-Induced Hypo- and Hyperprolactinemia in Children and Adolescents

[3] Stefan Leucht, et al. Am J Psychiatry. Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia

[4] Frank I Tarazi, et al. Expert Opin Pharmacother. Iloperidone, asenapine and lurasidone: a primer on their current status

[5] Leslie Citrome. Postgrad Med. Iloperidone, asenapine, and lurasidone: a brief overview of 3 new second-generation antipsychotics

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