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HT-2157

Cat. No. M14025
HT-2157 Structure
Synonym:

SNAP 37889

Size Price Availability Quantity
5mg USD 324  USD324 In stock
10mg USD 510  USD510 In stock
50mg USD 1500  USD1500 In stock
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Quality Control & Documentation
Biological Activity

HT-2157 (SNAP 37889) is a selective, high-affinity, competitive antagonists of galanin-3 receptor (Gal3).

Chemical Information
Molecular Weight 366.34
CAS Number 303149-14-6
Solubility (25°C) DMSO ≥ 29 mg/mL
Storage 2-8°C, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

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Keywords: HT-2157, SNAP 37889 supplier, inhibitors, activators

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