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Neuropeptide Y (human, rat, mouse) TFA

Cat. No. M55016
Neuropeptide Y (human, rat, mouse) TFA Structure
Size Price Availability Quantity
5mg USD 700  USD700 In stock
10mg USD 900  USD900 In stock
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Quality Control & Documentation
Biological Activity

Neuropeptide Y (human, rat, mouse) TFA is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.

Chemical Information
Molecular Weight 4385.70
Formula C191H286F3N55O59S
CAS Number 90880-35-6 (free base)
Solubility (25°C) Water ≥ 50 mg/mL
Storage -20°C, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

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