About 13 results found for searched term "MM 07" (0.201 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M11462 | IMM-H007 | AMPK |
| Imm-h007 is an adenosine derivative that is an activator of the AMP-Activated Protein Kinase (AMPK). | ||
| M21380 | MM 07 | Others |
| MM 07 is a biased apelin receptor agonist with a KD value of 300 nM in CHO-K cells and 172 nM in human heart. | ||
| M24695 | Clivatuzumab tetraxetan | Others |
| IMMU107 | ||
| Clivatuzumab tetraxetan (IMMU107) is a humanized anti-MUC1 monoclonal antibody. Clivatuzumab tetraxetan shows anti-tumor activity. Clivatuzumab tetraxetan has the potential for the research of metastatic pancreatic cancer. | ||
| M7647 | Bryostatin 1 | PKC |
| Bryostatin 1 is a natural macrolide isolated from the moss bug Bugula neritina and a potent PKC modulator of central nervous system (CNS) permeability.Bryostatin 1 binds to the isolated Munc13-1 C1 domain and the full-length Munc13-1 protein with a Ki value of 8.07 and 0.45 nM, respectively, and has anticancer, anti-inflammatory and neuroprotective activities. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with Ki values of 8.07 nM and 0.45 nM, respectively, and exhibits anticancer, anti-inflammatory, and neuroprotective activities. | ||
| M21336 | Recombinant Human MMP-9 (HEK293, C-6His) | Enzymes & Regulators |
| Matrix metalloproteinase-9; 92 kDa gelatinase; 92 kDa type IV collagenase | ||
| Recombinant human matrix metalloproteinase-9 is produced by a mammalian expression system and the target gene encoding Ala19-Asp707 has a 6His tag at the C-terminus. The proenzyme needs to be activated by APMA to form the active form. Protein ID: AAH06093.1. | ||
| M21570 | Recombinant Human CD3E (HEK293, C-6His) | Cytokines and Growth Factors |
| T-Cell Surface Glycoprotein CD3 Epsilon Chain | ||
| The recombinant human t cell surface glycoprotein CD3 Epsilon chain is produced by mammalian expression systems, and the target gene encoding Asp23-Asp126 is expressed by 6His tag at the C-terminal. Protein number: P07766. | ||
| M21571 | Recombinant Human CD3E (HEK293, C-mFc) | Cytokines and Growth Factors |
| T-Cell Surface Glycoprotein CD3 Epsilon Chain; T-Cell Surface Antigen T3/Leu-4 Epsilon Chain | ||
| The recombinant human t cell surface glycoprotein CD3 Epsilon chain is produced by mammalian expression systems, and the target gene encoding Gln22-Thr48 is expressed at the C-terminal using mouse IgG1 Fc tag. Protein number: P07766. | ||
| M21572 | Recombinant Human CD3E (HEK293, C-Fc) | Cytokines and Growth Factors |
| T-Cell Surface Glycoprotein CD3 Epsilon Chain; T-Cell Surface Antigen T3/Leu-4 Epsilon Chain | ||
| Recombinant human t cell surface glycoprotein CD3 Epsilon chain is produced by mammalian expression system, and the target gene encoding Asp23-Asp126 is expressed in the C-terminal human IgG1 Fc tag. Protein number: P07766. | ||
| M21573 | Recombinant Human/Cynomolgus CD28 (HEK293, N-6His) | Cytokines and Growth Factors |
| CD28; CD28 antigen; CD28 molecule | ||
| Recombinant human t cell specific surface glycoprotein CD28 is produced by mammalian expression systems, and the target gene encoding Asn19-Pro152 is expressed in the N-terminal with the 6His tag. Protein number: P10747. | ||
| M25003 | Talquetamab | Others |
| JNJ-64407564 | ||
| Talquetamab (JNJ-64407564) is a potentially first-in-class humanized IgG4ҡ/λ bispecific antibody that binds to GPRC5D (G-protein-coupled receptor family, group C5, member D) and CD3, and induces T-cell-mediated by T-cell recruitment and activation. killing of GPRC5-expressing MM cells through T cell recruitment and activation.Talquetamab (JNJ-64407564) has antitumor activity. | ||
| M29265 | PSB 0777 ammonium | Adenosine Receptor |
| PSB 0777 ammonium is a potent and selective adenosine A2A receptor full agonist with Ki values of 44.4 nM, 360 nM for rat and human A2A receptors, respectively. PSB 0777 ammonium has Ki values of ≥10000 nM, 541 nM for rat and human A1 receptors, respectively. PSB 0777 ammonium shows poor brain penetrant and perorally non-absorbable effect. PSB 0777 ammonium has the potential for inflammatory bowel disease (IBS) research research. | ||
| M29713 | CL075 | TLR |
| 3M002 | ||
| CL075 (3M002) is a selective TLR8 agonist with immunomodulating properties. CL075 triggers a MyD88-dependent signaling pathway to elicit production of inflammatory cytokines and type I interferons (IFNs) via activation of NF-κB and IRF7, respectively. | ||
| M45372 | NLRP3/AIM2-IN-3 | NLR |
| NLRP3/AIM2-IN-3 is a potent inhibitor that interferes with the interaction of NLRP3 or AIM2 with the bridging protein ASC and inhibits ASC oligomerization, and has different species-specific effects on NLRP3 and AIM2 inflammasome-dependent pyroptosis. In addition, NLRP3/AIM2-IN-3 inhibited LPS/nigericin-stimulated cell pyroptosis in THP-1 macrophages with an IC50 of 0.077 ± 0.008 μM. | ||
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