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Talquetamab

Cat. No. M25003

All AbMole products are for research use only, cannot be used for human consumption.

Talquetamab Structure
Synonym:

JNJ-64407564

Size Price Availability
1mg USD 350  USD350 Out of stock
5mg USD 875  USD875 Out of stock
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Quality Control & Documentation
Biological Activity

Talquetamab (JNJ-64407564) is a potentially first-in-class humanized IgG4ҡ/λ bispecific antibody that binds to GPRC5D (G-protein-coupled receptor family, group C5, member D) and CD3, and induces T-cell-mediated by T-cell recruitment and activation. killing of GPRC5-expressing MM cells through T cell recruitment and activation.Talquetamab (JNJ-64407564) has antitumor activity.

Chemical Information
CAS Number 2226212-40-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Ajai Chari, et al. N Engl J Med. Talquetamab, a T-Cell-Redirecting GPRC5D Bispecific Antibody for Multiple Myeloma

[2] Hélène Kaplon, et al. MAbs. Antibodies to watch in 2023

[3] Benjamin Tanenbaum, et al. Ann Hematol. The emerging therapeutic landscape of relapsed/refractory multiple myeloma

[4] Suzette Girgis, et al. Blood Adv. Effects of teclistamab and talquetamab on soluble BCMA levels in patients with relapsed/refractory multiple myeloma

[5] Christie P M Verkleij, et al. Blood Adv. Preclinical activity and determinants of response of the GPRC5DxCD3 bispecific antibody talquetamab in multiple myeloma

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Keywords: Talquetamab, JNJ-64407564 supplier, inhibitors, activators

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