About 21 results found for searched term "MBL-IN-1" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41078 | MBL-IN-1 | Antibiotic |
| MBL-IN-1 is a β-Lactamase inhibitor, with the IC50 ranging from 0.10 to 25.85 µM. | ||
| M3924 | Scrambled 10Panx | Peptides |
| Scrambled 10Panx is the scrambled form of 10Panx (WRQAAFVDSY), a mimetic peptide of pannexin 1 that inhibits dye uptake by macrophages without affecting cellular membrane currents. | ||
| M9112 | AB-423 | Anti-infection |
| AB-423 is an inhibitor of HBV capsid assembly, and potent inhibits HBV replication with EC50/EC90 of 0.08-0.27 μM/0.33-1.32 μM in cells. | ||
| M9119 | JNJ-632 | Anti-infection |
| JNJ632 | ||
| JNJ-632 is a potent HVV capsid assembly modulator and HBV replication inhibitor with EC50 of 100-200 nM for genotypes A-D. | ||
| M10204 | Tetraphenylporphyrin | Fluorescent Dye |
| TPP; Tetraphenylporphine | ||
| Tetraphenylporphyrin, abbreviated TPP or H2TPP, is a synthetic heterocyclic compound that resembles naturally occurring porphyrins. Porphyrins are dyes and cofactors found in hemoglobin and cytochromes and are related to chlorophyll and vitamin B12. | ||
| M21649 | Bractoppin | DNA/RNA Synthesis |
| Bractoppin is a potent and selective inhibitor of phosphopeptide recognition by the human BRCA1 tandem(t) BRCT domain with IC50 of 74 nM. Bractoppin diminishes BRCA1 recruitment to DNA breaks, in turn suppressing damage-induced G2 arrest and assembly of the recombinase, RAD51. | ||
| M29636 | MRL-494 | Antibiotic |
| MRL-494, an antibacterial agent, is a inhibitor of β-barrel assembly machine A (BamA) impervious to efflux and the outer membrane permeability barrier. MRL-494 can inhibits Gram-positive (MIC of 12.5 μM for Staphylococcus aureus COL) and Gram-negative (MIC of 25 μM for E. coli JCM158) bacterias. | ||
| M30624 | Avanbulin | Microtubule |
| BAL27862 | ||
| Avanbulin (BAL27862) is a potent, Colchicine site-binding, tubulin assembly inhibitor. Avanbulin inhibits tubulin assembly at 37 °C with an IC50 of 1.4 μM. Avanbulin binds to tubulin with an apparent Kd value of 244 nM. Avanbulin can be used for the research of cancer and cell division. | ||
| M30625 | KLD-12 | Peptides |
| KLD-12 is a 12-residue self-assembling peptide that can enhance chondrogenic differentiation of bone marrow stromal cells (BMSCs). KLD-12 hydrogel can fill full-thickness osteochondral defects in situ and improve cartilage repair. | ||
| M30996 | MRL-494 hydrochloride | Antibiotic |
| MRL-494 hydrochloride, an antibacterial agent, is a inhibitor of β-barrel assembly machine A (BamA) impervious to efflux and the outer membrane permeability barrier. MRL-494 hydrochloride can inhibits Gram-positive (MIC of 12.5 μM for Staphylococcus aureus COL) and Gram-negative (MIC of 25 μM for E. coli JCM158) bacterias. | ||
| M38848 | Larotaxel | Apoptosis |
| Larotaxel (XRP9881) exerts its cytotoxic effect by promoting tubulin assembly and stabilizing microtubules, ultimately leading to cell death by apoptosis. It presents the ability to cross the blood brain barrier and has a much lower affinity for P-glycoprotein 1 than Docetaxel. | ||
| M40539 | Dolastatin 15 | Microtubule |
| DLS15 | ||
| Dolastatin 15, a heptasubunit condensed peptide derived from Dolabella auricularia, is also a potent antimitotic agent and microtubule destabilizer that inhibits mitosis by blocking microtubule assembly. In addition, Dolastatin 15 induces cell cycle arrest and apoptosis in multiple myeloma cells. It can also be used as an ADC cytotoxin for ADC development studies. | ||
| M40719 | UNC9995 | Dopamine Receptor |
| UNC9995 is a novel β-arrestin 2-biased dopamine receptor Drd2 agonist that interferes with the assembly of inflammatory vesicles by enhancing the interaction of β-arrestin2 with NLRP3, thereby reducing IL-1β production. | ||
| M43195 | Nangibotide scrambled peptide | Others |
| Nangibotide scrambled peptide (LR12-scr) is a scrambled control peptide composed of the same amino acids from LR12 (Nangibotide) but in a random sequence (YQDVELCETGED). | ||
| M43200 | Tat-beclin 1 scrambled TFA | Others |
| Tat-beclin 1 scrambled TFA is the scrambled part and a scrambled control of Tat-beclin 1, which is derived from a region of the autophagy protein, beclin 1. | ||
| M43203 | Tat-beclin 1 scrambled | Others |
| Tat-beclin 1 scrambled is the scrambled part and a scrambled control of Tat-beclin 1, which is derived from a region of the autophagy protein, beclin 1. | ||
| M51372 | Prion Protein (106-126) (human) (scrambled) | Others |
| Prion Protein (106-126) (human) (scrambled) is a scrambled sequence of Prion Protein (106-126). | ||
| M55312 | Recombinant Human Decorin Protein (HEK293, C-6His) | Cytokines and Growth Factors |
| DCN | ||
| Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R. | ||
| M55313 | Recombinant Human Decorin Protein (HEK293) | Cytokines and Growth Factors |
| DCN | ||
| Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R. | ||
| M55314 | Recombinant Mouse Decorin Protein (HEK293, C-6His) | Cytokines and Growth Factors |
| DCN | ||
| Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R. | ||
| M55579 | GLP-26 | Anti-infection |
| GLP26 | ||
| GLP-26 is an HBV capsid assembly modulators (CAM), inhibits HBV DNA replication (IC50=3 nM) in Hep AD38 system, and reduces cccDNA by >90% at 1 μM. GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools. | ||
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