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Dolastatin 15, a heptasubunit condensed peptide derived from Dolabella auricularia, is also a potent antimitotic agent and microtubule destabilizer that inhibits mitosis by blocking microtubule assembly. In addition, Dolastatin 15 induces cell cycle arrest and apoptosis in multiple myeloma cells. It can also be used as an ADC cytotoxin for ADC development studies.
Molecular Weight | 837.06 |
Formula | C45H68N6O9 |
CAS Number | 123884-00-4 |
Form | Solid |
Storage | −20°C |
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