Product Name: | Dolastatin 15 |
Catalog Number: | M40539 |
CAS Number: | 123884-00-4 |
Formula: | C45H68N6O9 |
Molecular Weight: | 837.06 |
Form: | Solid |
Storage: | −20°C |
Chemical Structure: | ![]() |
QC Standard: | >99.0% |
H-NMR: | Consistent with structure |
Description: | Dolastatin 15, a heptasubunit condensed peptide derived from Dolabella auricularia, is also a potent antimitotic agent and microtubule destabilizer that inhibits mitosis by blocking microtubule assembly. In addition, Dolastatin 15 induces cell cycle arrest and apoptosis in multiple myeloma cells. It can also be used as an ADC cytotoxin for ADC development studies. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |