About 30 results found for searched term "IU1" (0.046 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2035 | IU1 | Proteasome |
| IU1 is a reversible, small molecule inhibitor of deubiquitination by USP14 that demonstrates an IC50 value of 4-5 μM. | ||
| M3009 | SGI-110 | DNA Methyltransferase |
| SGI-110 sodium; S-110 sodium | ||
| SGI-110 (S-110) is a stable and potent inhibitor for DNA methylation, inhibits DNMT1 when SGI-110 is activated by phosphorylation and incorporated into DNA. | ||
| M3173 | Potassium canrenoate | Mineralocorticoid Receptor |
| Aldadiene potassium, SC-14266 | ||
| Canrenoate potassium is a predrug for the release of Canrenone and an effective antagonist of competitive salt ocorticoid receptor. As a diuretic, Canrenoate potassium is used in the study of hypertension. | ||
| M3380 | Pitavastatin Calcium | Autophagy |
| Pitavastatin hemicalcium; NK-104 | ||
| Pitavastatin Calcium is a new type of statin. | ||
| M4968 | Mitiglinide calcium hydrate | Potassium Channel |
| KAD-1229 calcium hydrate; S-21403 calcium hydrate | ||
| Miglinide calcium hydrate is a compound used to study type 2 diabetes mellitus. It is a highly selective KATP channel antagonist. | ||
| M5405 | Amezinium methylsulfate | Adrenergic Receptor |
| Amezinium metilsulfate; Lu-1631 | ||
| Amezinium metilsulfate has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition ofnoradrenaline and tyramine uptake. | ||
| M5477 | Carbazochrome sodium sulfonate (AC-17) | Adrenergic Receptor |
| AC-17 | ||
| Carbazochrome sodium sulfonate (AC-17) is an antihemorrhagic for use in the treatment of hemorrhoids. | ||
| M5633 | Pantoprazole sodium | Proton Pump |
| SKF96022 sodium, BY-1023 sodium | ||
| Pantoprazole is a proton pump inhibitor drug that inhibits gastric acid secretion. It works on gastric parietal cells to irreversibly inhibit (H+/K+)-ATPase function and suppress the production of gastric acid. | ||
| M5667 | Fusidate Sodium | Antibiotic |
| Fucidin, Sodium fusidate, SQ-16360 | ||
| Fusidate Sodium is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections. | ||
| M8866 | Zonisamide sodium salt | Carbonic Anhydrase |
| AD 810 sodium; CI 912 sodium | ||
| Zonisamide sodium salt is an antiepileptic compound. | ||
| M9731 | Indoxyl sulfate potassium salt | Metabolite/Endogenous Metabolite |
| Potassium 1H-indol-3-yl sulfate | ||
| Indoxyl sulfate potassium salt (Potassium 1H-indol-3-yl sulfate) is a metabolite of tryptophan derived from dietary protein. | ||
| M10058 | Ethidium Homodimer 1 | Fluorescent Dye |
| EthD-1 | ||
| Ethidium Homodimer 1 (EthD-1) is a high-affinity fluorescent nucleic acid dye that binds ssDNA, dsDNA, RNA, oligonucleotides and triple helix DNA. | ||
| M10247 | Nesiritide acetate | Peptides |
| natriureticpeptide; BNP-32; 124584-08-3 | ||
| Nesiritide acetate is an agonist of natriuretic peptide receptors (NPRs), with Kd values of 7.3 and 13 pM for NPR-A and NPR-C, respectively. | ||
| M10358 | C-Type Natriuretic Peptide (CNP) (1-22), human | Angiotensin Receptor |
| CNP-22, human | ||
| C-Type Natriuretic Peptide (CNP) (1-22), human is the 1-22 fragment of C-Type Natriuretic Peptide. | ||
| M10504 | IU1-47 | Deubiquitinase |
| IU 1-47 | ||
| IU1-47 is a potent and specific USP14 inhibitor with an IC50 of 0.6 μM. | ||
| M13588 | Methotrexate disodium | Antifolate |
| Amethopterin disodium; CL14377 disodium; WR19039 disodium | ||
| Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. | ||
| M13957 | Carperitide acetate | Endothelin Receptor |
| Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate | ||
| Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. | ||
| M14494 | Sodium metatungstate | Pyroptosis |
| Sodium polyoxotungstate; POM-1 | ||
| Sodium metatungstate (Sodium polyoxotungstate) is a potent ecto-nucleoside triphosphate diphosphohydrolase (ENTPDase) inhibitor, with Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1 (CD39), NTPDase 3 and NTPDase 2 respectively. | ||
| M14825 | Sincalide ammonium | Peptides |
| Cholecystokinin octapeptide ammonium; CCK-8 ammonium; SQ19844 ammonium | ||
| Sincalide ammonium (Cholecystokinin octapeptide ammonium) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. | ||
| M21623 | Clavulanate Potassium | Antibiotic |
| Potassium Clavulanate-Microcrystalline cellulose(1:1) | ||
| Clavulanate potassium is a potent β-lactamase inhibitor and acts as an antibiotic. | ||
| M27846 | Fondaparinux sodium | Factor Xa |
| Fondaparin sodium; SR-90107A | ||
| Fondaparinux sodium is a synthetic pentasaccharide and indirect factor Xa inhibitor that mimics the structure of the heparin binding site and has a very high affinity for factor Xa, binding to AT and accelerating its inhibition of factor Xa. | ||
| M28171 | Olodanrigan sodium | Angiotensin Receptor |
| EMA401 sodium; PD-126055 sodium | ||
| Olodanrigan (EMA401) sodium is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. Olodanrigan sodium is under development as a neuropathic pain therapeutic agent. Olodanrigan sodium analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. | ||
| M28227 | Vidofludimus hemicalcium | DHODH |
| 4sc-101 hemicalcium; SC12267 hemicalcium | ||
| Vidofludimus (4sc-101; SC12267) hemicalcium is an orally active inhibitor for dihydroorotate dehydrogenase (DHODH) and also is a novel modulator for farnesoid X receptor (FXR). Vidofludimus hemicalcium, as an immunomodulatory agent, can be used for the research of autoimmune disorders such as inflammatory bowel disease (IBD). Vidofludimus hemicalcium also can be used for the research of fatty liver by targeting FXR. | ||
| M28561 | Afabicin disodium | Antibiotic |
| Debio 1450 disodium; AFN-1720 disodium | ||
| Afabicin (Debio 1450) is the proagent of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci. | ||
| M29497 | IU1-248 | Deubiquitinase |
| IU1-248, a derivative of IU1, is a potent and selective USP14 inhibitor with an IC50 of 0.83 μM. | ||
| M31152 | Sodium L-lactate-13C3 solution | Others |
| Sodium L-lactate-13C3 solution is a 13C-labeled L-lactate that can be used in studies related to lactate metabolism. | ||
| M44022 | Trimethylvinylammonium(1+) | Others |
| Trimethylvinylammonium(1+) | ||
| M45070 | Sodium 8-(phenylamino)naphthalene-1-sulfonate | Fluorescent Dye |
| Sodium 8-(phenylamino)naphthalene-1-sulfonate is a hydrophobic azo dye. | ||
| M50240 | Heparin sodium salt (MW 15kDa) | Animal Modeling |
| Sodium heparin (MW 15kDa); Sodium heparinate (MW 15kDa) | ||
| Heparin sodium salt (MW 15kDa) is a heparin polymer with a molecular weight of 15kDa.Heparin sodium salt is an anticoagulant that reversibly binds to antithrombin III (ATIII), thereby accelerating the rate of inactivation of Thrombin factor IIa and factor Xa by ATIII. Heparin sodium salt is used for blood collection and plasma preparation in experimental animals and for the construction of parenteral nutrition models in mice. | ||
| M52624 | Atrial natriuretic factor (1-28) (human, porcine) | Metabolite/Endogenous Metabolite |
| Atrial natriuretic factor (1-28) (human, porcine) is a potent suppressor of pro-opiomelanocortin (POMC) mRNA but a weak inhibitor of βEP-LI release. | ||
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