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Indoxyl sulfate potassium salt (Potassium 1H-indol-3-yl sulfate) is a metabolite of tryptophan derived from dietary protein. Indoxyl sulfate potassium salt (250 µM) can induce the activation of NF-κB, promoting the expression of both TGF-β1 and Smad3 expression in proximal tubular cells of rats.
| Molecular Weight | 251.3 |
| Formula | C8H6KNO4S |
| CAS Number | 2642-37-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 70 mg/mL Water 30 mg/mL |
| Storage | Powder -20°C |
| Related Metabolite/Endogenous Metabolite Products |
|---|
| p-Cresol glucuronide
p-Cresol glucuronide is a metabolite of p-cresol, it is a prototype protein-bound uremic toxin. |
| Oleamide
Oleamide is an endogenous fatty acid amide. |
| Deoxycarnitine chloride
Deoxycarnitine chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota. |
| Monobutyl phthalate
Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant. |
| Testosterone sulfate (pyridinium)
Testosterone sulfate pyridinium is a Testosterone sulfate with a pyridinium. Testosterone sulfate is the metabolite of Testosterone. |
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