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Olodanrigan (EMA401) sodium is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. Olodanrigan sodium is under development as a neuropathic pain therapeutic agent. Olodanrigan sodium analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons.
Molecular Weight | 529.56 |
Formula | C32H28NNaO5 |
CAS Number | 1316755-17-5 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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