About 1 result found for searched term "1316755-17-5" (0.123 seconds)
Cat.No. | Name | Target |
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M28171 | Olodanrigan sodium | Angiotensin Receptor |
EMA401 sodium; PD-126055 sodium | ||
Olodanrigan (EMA401) sodium is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. Olodanrigan sodium is under development as a neuropathic pain therapeutic agent. Olodanrigan sodium analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. |
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