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Losartan potassium is a selective non-peptide angiotensin AT1 receptor antagonist. Losartan potassium inhibits the contractile effects of angiotensin II on rabbit aorta and jugular vein (pA2 = 8.27). Losartan potassium is an angiotensin II receptor antagonist drug.
| Molecular Weight | 462.01 |
| Formula | C22H23ClKN6O |
| CAS Number | 124750-99-8 |
| Solubility (25°C) | DMSO 78 mg/mL Water 39 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Abdul-Rahman A Al-Majed, et al. Losartan: Comprehensive Profile
[3] Domenic A Sica, et al. Clinical pharmacokinetics of losartan
[4] L M Burrell. A risk-benefit assessment of losartan potassium in the treatment of hypertension
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