About 30 results found for searched term "HA-IN-1" (0.037 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2197 | Sulfasalazine | Ferroptosis |
| Salazopyrin; Azulfidine; Sulphasalazine; SAS; NSC 667219 | ||
| Sulfasalazine is a sulfonamide agent derived from Mesalazine. Sulfasalazine has xC-system inhibitory activity associated with iron death and is primarily used as an anti-inflammatory agent. Sulfasalazine can suppress NF-κB activity. Sulfasalazine is a type 1 ferroptosis inducer. | ||
| M3942 | Cephalotaxine | Anti-infection |
| (-)-Cephalotaxine; ZINC19795976 | ||
| Cephalotaxine is a benzazepine alkaloid isolated from Cephalotaxus harringtonia. | ||
| M4822 | Eltrombopag Olamine | Thrombopoietin/Thrombin |
| Eltrombopag diethanolamine salt; SB-497115GR | ||
| Eltrombopag olamine is a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. | ||
| M5944 | Ruxolitinib phosphate | JAK |
| INCB018424 phosphate; INCB 018424 phosphate; INCB-018424 phosphate; Ruxolitinib | ||
| Ruxolitinib phosphate(INCB018424 phosphate) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. | ||
| M8253 | Mifamurtide | Others |
| CGP-19835; MTP-PE; MTP-cephalin; CGP19835; L-MTP-PE; MLV19835 | ||
| Mifamurtide (Muramyl tripeptide phosphatidylethanolamine; MTP-cephalin; MTP-PE) is a synthetic, lipophilic analog of muramyl dipeptide. | ||
| M9126 | Ac-CoA Synthase Inhibitor 1 | Anti-infection |
| Ac-CoA Synthase Inhibitor I | ||
| Ac-CoA Synthase Inhibitor 1 (also known as ACSS2 Inhibitor), an anti-virus agent, is a Ac-CoA Synthase Inhibitor. | ||
| M9403 | TPI-1 | Phosphatase |
| Tyrosine Phosphatase Inhibitor 1 | ||
| TPI-1 is a SHP-1 inhibitor, inhibits recombinant SHP-1 with an IC50 of 40 nM. | ||
| M10080 | Saccharin 1-methylimidazole | DNA/RNA Synthesis |
| SMI | ||
| Saccharin 1-methylimidazole (also known as SMI) is an activator for DNA and RNA synthesis. | ||
| M10592 | Recombinant Human M-CSF (CHO) | Cytokines and Growth Factors |
| Recombinant Human Macrophage Colony-stimulating Factor; CSF-1; rHM-CSF | ||
| Human M-CSF protein (CHO) is a hematopoietic growth factor with multiple glycoylation sites, which can affect the survival and function of macrophages and has antitumor activity. It was expressed by CHO cells. | ||
| M11485 | Recombinant Mouse GM-CSF Protein (E. coli) | Cytokines and Growth Factors |
| Granulocyte Macrophage Colony Stimulating Factor; CSF-2; MGI-1GM | ||
| Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory. ED50 < 5.0 pg/ mL, measured in cell proliferation assay of mouse FDC-P1 cells, corresponding specific activity > 2.0 × 108 units/mg. | ||
| M15025 | Recombinant Mouse MIP-1α/CCL3 (HEK 293) | Cytokines and Growth Factors |
| Macrophage Inflammatory Protein-1α; CCL-3; LD78α; LD78 alpha | ||
| MIP-1 Alpha, also known as CCL3, G0S19-1 and SCYA3, LD78 Alpha, is an inflammatory chemokine. Mip-1 α belongs to the CCL chemokine family and has 68% homology with MIP-1β. The mature form of MIP-1α contains 69 amino acids, which are present in solution as dimers and tend to accumulate reversibly. Protein structure: MIP-1α (ALA24-ALA92), Accession # : Q5QNW0. | ||
| M15024 | Recombinant Human MIP-1α/CCL3 (CHO) | Cytokines and Growth Factors |
| Macrophage Inflammatory Protein-1α; CCL-3; LD78α; LD78 alpha | ||
| Mip-1 Alpha, also known as CCL3, G0S19-1 and SCYA3, LD78 Alpha, is an inflammatory chemokine. Mip-1 α belongs to the CCL chemokine family and has 68% homology with MIP-1β. The mature form of MIP-1α contains 69 amino acids, which are present in solution as dimers and tend to accumulate reversibly. Protein structure: MIP-1α (ALA27-ALA92), Accession # : P10147. | ||
| M15026 | Recombinant Human MIP-1β /CCL4 (E. coli) | Cytokines and Growth Factors |
| MIP-1 beta; Macrophage Inflammatory Protein-1β; CCL-4; ACT-2 | ||
| Macrophage inflammatory protein 1β (MIP-1β), also known as Chemokine (C-motif) ligand 4 (CCL4), is a small cytokine in the CC Chemokine family. It is a chemical attractant for natural killer cells, monocytes and a variety of other immune cells. Protein structure: MIP-1β (ALA24-ASN92), Accession # P13236-1. | ||
| M14089 | IFN alpha-IFNAR-IN-1 hydrochloride | Interferon-α/β/γ |
| IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR; inhibit MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM). | ||
| M14457 | FX-11 | LDH |
| LDHA Inhibitor FX11 | ||
| FX-11 (LDHA Inhibitor FX11) is a potent lactate dehydrogenase A (LDHA) inhibitor with an IC50 of 23.3 μM for HeLa cell and a Ki value of 8 μM. FX-11 can reduce ATP levels, induce oxidative stress and ROS production, and cause cell death. | ||
| M17927 | tert-Butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazine-1-carboxylate | Others |
| tert-Butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazine-1-carboxylate | ||
| M21719 | Recombinant Human GDF-15/MIC-1 Protein (E. coli) | Cytokines and Growth Factors |
| Growth/Differentiation Factor 15 / Macrophage Inhibitory Cytokine 1 | ||
| The recombinant human GDF-15/MIC-1 is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. | ||
| M24563 | Telimomab aritox | Others |
| T101-ricin A chain immunotoxin T101-RTA | ||
| Telimomab aritox (T101-ricin A chain immunotoxin) is a mouse monoclonal antibody that linked to the A chain of the ricin protein. Telimomab aritox can be used as an immunosuppressive agent. | ||
| M29724 | Glucosylceramide synthase-IN-1 | Glucosylceramide Synthase |
| Glucosylceramide synthase-IN-1 (T-036) a potent, brain-penetrant and orally active glucosylceramide synthase (GCS) inhibitor with IC50s of 31 nM and 51 nM for human GCS and mouse GCS, respectively. Glucosylceramide synthase-IN-1 can be used for Gaucher's disease research. | ||
| M29822 | Aha1/Hsp90-IN-1 | Microtubule |
| Aha1/Hsp90-IN-1 (Compound 17) is an Aha1/Hsp90 complex inhibitor. Aha1/Hsp90-IN-1 disrupts Aha1/Hsp90 interactions with an IC50 of 3.32 μM. Aha1/Hsp90-IN-1 inhibits tau aggregation. | ||
| M30493 | KV2 channel inhibitor-1 | Potassium Channel |
| KV2 channel inhibitor-1 is a selective KV2 channel inhibitor with IC50s of 0.2 μM and 0.41 μM for KV2.1 and KV2.2, respectively. KV2 channel inhibitor-1 possesses good selectivity over KV1.2 (IC50>10 μM). KV2 channel inhibitor-1 is >10-fold selective over NaV channels and other KV channels and displays weak activity on CaV channels. | ||
| M39080 | Lysophosphatidylcholine 18:2 | Metabolite/Endogenous Metabolite |
| Lysophosphatidylcholine 18:2 (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC), a lysophospholipid, is a potential biomarker identified from insulin resistance (IR) polycystic ovary syndrome (PCOS). | ||
| M41137 | Chitin synthase inhibitor 13 | Antifungal |
| Chitin synthase inhibitor 13 is a non-competitive inhibitor of chitin synthase, with an IC50 of 106.7 μM. | ||
| M41203 | HA-IN-1 | Anti-infection |
| HA-IN-1 is a Hemagglutinin (HA) ligand with high affinity, targeting to the trypsin cleavage site of HA. | ||
| M42250 | Nav1.3 channel inhibitor 1 | Sodium Channel |
| Nav1.3 channel inhibitor 1 is a state-dependent voltage-gated sodium channel Nav1.3 inhibitor (IC50=20 nM). | ||
| M42551 | Phosphatase-IN-1 | Phosphatase |
| Phosphatase-IN-1 derivative, is a phosphatidate phosphatase (Pah) inhibitor. | ||
| M42649 | hAChE/hBACE-1-IN-1 | AChR/AChE |
| hAChE/hBACE-1-IN-1 is an orally active inhibitor of hAChE with blood-brain permeability. | ||
| M42662 | hAChE-IN-1 | AChR/AChE |
| hAChE-IN-1 is a potent hAChE inhibitor with an IC50 of 1.09 μM. | ||
| M42952 | Squalene synthase-IN-1 | Others |
| Squalene synthase-IN-1 is a potent antihyperlipidemic agent acting through Squalene Synthase inhibition. | ||
| M44495 | 3beta-(alpha-L-Arabinopyranosyloxy)urs-12,18-dien-28-oic acid beta-D-glucopyranosyl ester | Others |
| 3beta-(alpha-L-Arabinopyranosyloxy)urs-12,18-dien-28-oic acid beta-D-glucopyranosyl ester | ||
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