About 27 results found for searched term "FMK" (0.077 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2710 | FMK | S6 Kinase |
| RSK2 kinase inhibitor | ||
| FMK is a potent and selective inhibitor of p90 ribosomal protein S6 kinaseRSK2 (wt) with IC50 of 15 nM, >600- and 200-fold selectivity for RSK2 than the C436V and T493M mutants. | ||
| M3134 | Z-DEVD-FMK | Caspase |
| Caspase-3 Inhibitor | ||
| Z-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor with an IC50 of 18 μM, and also shows potent inhibition on caspase-6, caspase-7, caspase-8, and caspase-10. | ||
| M3136 | Z-IETD-FMK | Caspase |
| Caspase-8 Inhibitor; Z-IE(OMe)TD(OMe)-FMK | ||
| Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective and cell permeable caspase-8 inhibitor. Z-IETD-FMK is also a granzyme B inhibitor. | ||
| M3143 | Z-VAD-FMK | Caspase |
| Z-VAD(OH)-FMK | ||
| Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor which blocks all features of apoptosis. | ||
| M6128 | BOC-D-FMK | Caspase |
| Boc-D-FMK is a cell-permeable, irreversible and broad spectrum caspase inhibitor; inhibits apoptosis stimulated by TNF-α with an IC50 of 39 µM. | ||
| M6231 | Z-VAD(OH)-FMK | Caspase |
| Z-VAD-FMK (Caspase Inhibitor VI) is an irreversible pan-caspase inhibitor. | ||
| M6232 | Z-LEED-FMK | Caspase |
| Z-LEED-FMK is caspase-13 inhibitor. | ||
| M6233 | Z-YVAD-FMK | Caspase |
| Z-YVAD-FMK is a synthetic peptide that irreversibly inhibits activity of caspase-1. The inhibitor is designed as a methyl ester to facilitate cell permeability. The product can be used for both in vitro and in vivo studies. | ||
| M6234 | Z-FA-FMK | Caspase |
| Z-FA-FMK is an irreversible cysteine protease inhibitor, and also inhibits effector caspases. | ||
| M9486 | N-BOC-D-FMK | Caspase |
| Boc-Asp(OMe)-fluoromethyl ketone; Boc-Asp(OMe)-FMK; Boc-D(OMe)-FMK | ||
| N-BOC-D-FMK (Boc-D(OMe)-FMK) is a broad range caspase inhibitor. N-BOC-D-FMK inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8. | ||
| M13538 | Z-WEHD-FMK | Caspase |
| Z-WEHD-FMK is a potent, cell-permeable and irreversible caspase-1/5 inhibitor. Z-WEHD-FMK also exhibits a robust inhibitory effect on cathepsin B activity (IC50=6 μM). Z-WEHD-FMK can be used to investigate cells for evidence of apoptosis. | ||
| M13564 | FMK 9a | Autophagy |
| FMK 9a is an autophagin-1 inhibitor with IC50 values of 80 and 73 μM in FRET and LRA assay. | ||
| M22359 | FMK-MEA | Others |
| FMK-MEA | ||
| M22509 | Z-VRPR-FMK | MALT1 |
| Z-VRPR-FMK is an irreversible MALT1 protein inhibitor. Z-VRPR-FMK inhibits the growth and invasion of diffuse large B-cell lymphoma by inhibiting MALT1-induced NF-κB activation and MMP expression. | ||
| M30240 | Z-LEHD-FMK TFA | Caspase |
| Z-LEHD-FMK TFA is a selective and irreversible inhibitor of caspase-9, protects against lethal reperfusion injury and attenuates apoptosis. Z-LEHD-FMK TFA exhibits the neuroprotective effect in a rat model of spinal cord trauma. | ||
| M41361 | Z-LLY-FMK | Proteasome |
| Z-LLY-FMK (Calpain Inhibitor IV) is a calpain inhibitor, involved in apoptosis of many cell systems. | ||
| M42304 | Ac-VLPE-FMK | Cathepsin |
| Ac-VLPE-FMK, a tetrapeptidyl mono-fluoromethyl ketone (m-FMK), is a Cat-B and Cat-L inhibitor. | ||
| M42999 | Ac-PLVE-FMK | Others |
| Ac-PLVE-FMK (Ac-Pro-Leu-Val-Glu(OMe)-CH2F), a tetrapeptidyl m-FMKs, is a Cats inhibitor. | ||
| M45397 | Z-LEVD-FMK | Caspase |
| Z-LEVD-FMK is a cell-permeable Caspase-4 inhibitor that blocks ER stress-induced apoptosis in cancer cells. | ||
| M52648 | Z-FF-FMK | Cathepsin |
| Z-FF-FMK is a selective cathepsin-L inhibitor. | ||
| M52671 | (S, S)-Z-FA-FMK | Cathepsin |
| (S,S)-Z-FA-FMK is a cell-permeable, irreversible cathepsin B inhibitor. | ||
| M53396 | Z-LE(OMe)TD(OMe)-FMK | Caspase |
| Z-LE(OMe)TD(OMe)-FMK is a selective caspase-8 inhibitor. | ||
| M53407 | Z-VEID-FMK | Caspase |
| Z-VEID-FMK (Z-VE(OMe)ID(OMe)-FMK) is a selective and irreversible caspase-6 peptide inhibitor. | ||
| M53408 | Z-LEED-FMK | Caspase |
| Z-LEED-FMK is a caspase-13 and caspase-4 inhibitor. | ||
| M53846 | Z-VDVAD-FMK | Caspase |
| Z-VDVAD-FMK is a special inhibitor of caspase-2. | ||
| M56679 | AFMK | Metabolite/Endogenous Metabolite |
| AFMK, antioxidant metabolite of Melatonin, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice. | ||
| M57717 | Biotin-VAD-FMK | Others |
| Biotin-VAD-FMK | ||
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