About 30 results found for searched term "EP6" (0.018 seconds)
Cat.No. | Name | Target |
---|---|---|
M1834 | Omeprazole (H 16868) | Proton Pump |
H 16868; Omeprazol | ||
Omeprazol is a first-in-class proton pump inhibitor (PPI) used in the treatment of dyspepsia, laryngopharyngeal reflux (LPR) and Zollinger–Ellison syndrome. | ||
M1859 | RepSox (ALK5 Inhibitor II) | ALK |
RepSox; E-616452; SJN 2511; 616452 | ||
RepSox (ALK5 Inhibitor II) is a potent and ATP-competitive inhibitor of the TGF-β type I receptor ALK5 (IC50 values are 0.004 and 0.023 μM for ALK5 autophosphorylation and ALK5 binding respectively). | ||
M2007 | Romidepsin (FK228) | HDAC |
FK228; ISTODAX; Depsipeptide; FR 901228; NSC 630176 | ||
Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a structurally unique, potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.*The compound is unstable in solutions, freshly prepared is recommended | ||
M2045 | CEP-32496 | Raf |
RXDX-105; Agerafenib | ||
CEP-32496 is a potent orally active BRAF inhibitor with IC50 of 14 nM. | ||
M2179 | EPZ-5676 | Histone Methyltransferase |
Pinometostat | ||
EPZ-5676 is a potent and selective aminonucleoside inhibitor of DOT1L histone methyltransferase. | ||
M2676 | EPZ005687 | EZH2 |
EPZ005687 is a potent, selective EZH2 inhibitor,Ki The value is 24 nM, which is 50 times more selective than EZH1 and 500 times more selective than 15 other methyltransferases. | ||
M3447 | PF-2545920 | PDE |
Mardepodect; CAS# 898562-94-2 | ||
PF-2545920 is a potent and selective PDE10A inhibitor with IC50 of 0.37 nM, with >1000-fold selectivity over the PDE. | ||
M3942 | Cephalotaxine | Anti-infection |
(-)-Cephalotaxine; ZINC19795976 | ||
Cephalotaxine is a benzazepine alkaloid isolated from Cephalotaxus harringtonia. | ||
M4954 | EPZ015666 | PRMTs |
GSK3235025 | ||
EPZ015666 is a potent, selective and orally bioavailable PRMT5 inhibitor with Ki of 5 nM, >20,000-fold selectivity over other PMTs. | ||
M5160 | Reparixin | CXCR |
Repertaxin; DF 1681Y | ||
Reparixin is a noncompetitive allosteric inhibitor of IL-8 (CXCL8) activation of CXCR1 and CXCR2 chemokine receptors with IC50 of 1 and 100 nM, respectively. | ||
M5373 | 6-Aminocaproic acid | Others |
EACA; Epsilon-Amino-n-caproic Acid; 6-Aminohexanoic acid | ||
6-Aminocaproic acid (EACA) is a derivative and analogue of the amino acid lysine, it is also a potent and orally active inhibitor of plasmin and plasminogen. | ||
M5499 | Cefradine | Antibiotic |
Cephradine; SQ-11436 | ||
Cefradine is a first generation cephalosporin antibiotic. | ||
M6278 | Epothilone D | Microtubule |
12,13-Desoxyepothilone B; Desoxyepothilone B; KOS 862 | ||
Epothilone D is a potent microtubule stabilizer. | ||
M6336 | 3-Deazaneplanocin A hydrochloride | Histone Methyltransferase |
DZNep hydrochloride; NSC 617989 hydrochloride; 3-Deazaneplanocin hydrochloride | ||
3-Deazaneplanocin A hydrochloride(DZNep HCl) is a eZH2 histone methyltransferase inhibitor. | ||
M6504 | Olcegepant (BIBN-4096) | CGRP Receptor |
BIBN-4096; BIBN 4096BS | ||
Olcegepant (BIBN-4096) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide (CGRP) receptor with IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP. | ||
M7904 | Methiothepin mesylate salt | Others |
Metitepine mesylate; Ro 8-6837 mesylate | ||
Methiothepin mesylate salt is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors. | ||
M8649 | GSK591 | PRMTs |
GSK-591; GSK3203591; EPZ015866 | ||
GSK591 (EPZ015866) is a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) with an IC50 of 4 nM. | ||
M9001 | ML-265 (TEPP-46) | Pyruvate Kinase |
TEPP-46; ML265 | ||
Ml-265 (TEPP-46) is an effective activator of pyruvate kinase M2 (PKM2). | ||
M9420 | GSK3326595 | PRMTs |
EPZ015938; GSK-3326595 | ||
GSK3326595 is a potent, reversible and selective protein arginine methyltransferase 5 (PRMT5) inhibitor with broad antiproliferative activity for studies related to lymphoma and leukemia. | ||
M9567 | Leptin (116-130) mouse | Others |
LEP(116-130) mouse | ||
Leptin (116-130) mouse is a synthetic leptin peptide fragment. | ||
M9853 | Brepocitinib P-Tosylate | JAK |
CS-2860; Brepocitinib;PF-06700841 P-Tosylate | ||
PF-06700841 (Brepocitinib) tosylate is a dual inhibitor of JAK1 and TYK2, with IC50 values of 17 nM and 23 nM, respectively. | ||
M10233 | ((Cys31,Nva34)-Neuropeptide Y (27-36))2 | Neuropeptide Receptor |
BWX 46 | ||
((Cys31,Nva34)-Neuropeptide Y (27-36))2, also called BWX 46, is a neuropeptide Y (NPY) Y5 receptor selective agonist. | ||
M10427 | OVA Peptide (257-264) TFA | Peptides |
OVA Peptide (257-264) TFA is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb. | ||
M10489 | NEO2734 (EP31670) | Epigenetic Reader Domain |
EP31670; NEO-2734 | ||
NEO2734 (EP31670) is a novel, orally active and selective dual inhibitor of p300/CBP and BET bromodomain with IC50 of both <30 nM. | ||
M10532 | Tazemetostat hydrobromide | Histone Methyltransferase |
EPZ-6438 hydrobromide; Tazemetostat HBr | ||
Tazemetostat (EPZ-6438) hydrobromide is a first-in-class potent, selective and orally available EZH2 inhibitor. | ||
M10961 | Ralaniten triacetate | Androgen Receptor |
EPI-506 | ||
Ralaniten triacetate (EPI-506), a prodrug for Ralaniten, is a pioneering, orally active androgen receptor (AR) N-terminal domain (NTD) inhibitor. Ralaniten triacetate is active against full-length and resistance-related AR species, including AR-v7. | ||
M11319 | GLP-1(7-36), amide TFA | GLP Receptor |
Glucagon-like peptide-1 (GLP-1)(7-36), amide TFA; Human GLP-1 (7-36), amide TFA | ||
TFA is a major intestinal hormone that stimulates insulin secretion by pancreatic beta cells in response to glucose. | ||
M25417 | Masofaniten | Androgen Receptor |
Androgen receptor-IN-2; EPI-7386 | ||
Masofaniten (Androgen receptor-IN-2) is a potent and orally active androgen receptor inhibitor. Masofaniten inhibits androgen binding to androgen receptor with IC50 of 535 nM in the androgen-induced PSA-Luciferase assay. | ||
M13968 | GLP-1(7-36), amide acetate | GLP Receptor |
Glucagon-like peptide-1 (GLP-1)(7-36), amide acetate; Human GLP-1 (7-36), amide acetate | ||
GLP-1(7-36), amide acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells. | ||
M14026 | Peptide YY (PYY) (3-36), porcine TFA | Others |
Peptide YY (PYY) (3-36), porcine TFA is a gut hormone peptide that acts as a Y2 receptor agonist to reduce appetite. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.