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TRAP-6

Cat. No. M9771

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TRAP-6 Structure
Synonym:

Thrombin Receptor Activator Peptide 6; PAR-1 agonist peptide

Size Price Availability Quantity
1mg USD 40  USD40 In stock
5mg USD 100  USD100 In stock
10mg USD 150  USD150 In stock
25mg USD 340  USD340 In stock
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Quality Control & Documentation
Biological Activity

TRAP-6 (Thrombin Receptor Activator Peptide 6) is a peptide fragment (residues 42-47) of protease-activated receptor 1 (PAR1) that acts as a PAR1 agonist. TRAP-6 stimulates platelet aggregation, promotes intracellular Ca2+ mobilization, and induces rapid phosphodiesterase 3A (PDE3A).

Chemical Information
Molecular Weight 748.87
Formula C34H56N10O9
CAS Number 141136-83-6
Solubility (25°C) Water ≥ 28 mg/mL
DMSO ≥ 20 mg/mL
Storage -20°C, dry, sealed
References

[1] Trivendra Tripathi, et al. Invest Ophthalmol Vis Sci. Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells

[2] Christoph Schimmer, et al. Thorac Cardiovasc Surg. The predictive value of multiple electrode platelet aggregometry (multiplate) in adult cardiac surgery

[3] Bruce E Maryanoff, et al. Curr Med Chem Cardiovasc Hematol Agents. Discovery of potent peptide-mimetic antagonists for the human thrombin receptor, protease-activated receptor-1 (PAR-1)

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Keywords: TRAP-6, Thrombin Receptor Activator Peptide 6; PAR-1 agonist peptide supplier, Peptides, inhibitors, activators

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