About 30 results found for searched term "CC4" (0.037 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1976 | Pomalidomide | Ligand for E3 Ligase |
| Actimid, CC-4047 | ||
| Pomalidomide is the third-generation immunomodulatory agent, functions through interacting with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors. Pomalidomide is a second generation immunomodulator, TNF-α inhibitor with IC50 of 13 nM. | ||
| M2030 | Apremilast | PDE |
| CC-10004 | ||
| Apremilast is a novel, orally available small molecule inhibitor of PDE4 with IC50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC50 of 104 nM. | ||
| M2129 | Temozolomide | DNA/RNA Synthesis |
| NSC362856; CCRG81045; TMZ | ||
| Temozolomide (TMZ) is an oral DNA methylating, chemotherapeutic agent. | ||
| M2498 | CCG 50014 | Others |
| CCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM. | ||
| M3921 | Dioscin | Autophagy |
| CCRIS 4123, Collettiside III | ||
| Dioscin (CCRIS 4123, Collettiside III) is a natural steroid saponin derived from several plants, showing potent anti-cancer effect against a variety of tumor cell lines. | ||
| M5156 | CCT241533 hydrochloride | Checkpoint |
| CCT241533 HCl | ||
| CCT241533 hydrochloride is a potent serine/threonine checkpoint kinase (Chk2) inhibitor with IC50 of 3 nM. | ||
| M6568 | CCG 2046 | Others |
| CCG 2046 is a inhibitor of regulator of G-protein signaling 4 (RGS4). | ||
| M6744 | Ganaxolone | GABA Receptor |
| CCD 1042 | ||
| Ganaxolone (CCD 1042) is A neuroactive steroid allopregnenolone analogue synthesized orally and is A selective, high-affinity positive sex modulator of γ -aminobutyrate-A (GABAA) receptor with anticonvulsant properties. Gannadone works through different binding sites with benzodiazepine binding sites and can be used in epilepsy studies related to cyclin-dependent kinase-like 5 (CDKL5) deficiency (CDD). | ||
| M8083 | MCC950 sodium salt (CP-456773) | Pyroptosis |
| CP-456773 sodium; CRID3 sodium salt | ||
| MCC950 (CP-456773) sodium salt is a potent, selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively. MCC950 specifically inhibits NLRP3 but not AIM2, NLRC4 or NLRP1 activation. | ||
| M8243 | CCT036477 | Others |
| CCT036477 is an inhibitor of Wnt signaling. | ||
| M8525 | CCT031374 hydrobromide | Others |
| CCT031374 is an inhibitor of TCF-dependent transcription. | ||
| M8686 | CCF642 | Apoptosis |
| CCF642 is a cell-permeable protein disulfide isomerase (PDI) inhibitor that exhibits 100-fold higher potency than PACMA 31 (by di-E-GSSG assay) via an alternative mode of action that most likely involves PDI active-site CGHCK motifs instead of cysteine known to be targeted by PACMA 31. | ||
| M8986 | CCX140 | CCR |
| CCX140-B | ||
| CCX140 is a potent CCR2 antagonist. | ||
| M8999 | CCG-1423 | Ras |
| CCG-1423 is a novel specific inhibitor of RhoA transcriptional signaling. | ||
| M9023 | Ellipticine | Topoisomerase |
| CCG36483; NSC71795 | ||
| Ellipticine is a DNA intercalating agent and a DNA topoisomerase II inhibitor. | ||
| M9521 | Glumetinib | c-Met |
| SCC244 | ||
| Glumetinib, also known as SCC244, is a novel, potent and highly selective inhibitor of c-Met with an IC50 of 0.42 nM. | ||
| M9720 | Aranidipine | Calcium Channel |
| MPC1304; CCRIS-6724 | ||
| Aranidipine (MPC1304) is a calcium channel blocker which may positively affect ambulatory blood pressure. *This compound is unstable in solutions, freshly prepared is recommended. | ||
| M10129 | CCT245737 | Checkpoint |
| SRA737; PNT-737 | ||
| CCT245737 is a potent, selective and orally active checkpoint kinase 1 (CHK1) inhibitor, with IC50 values of 1.3 nM, 2440 nM and 30 nM for CHK1, CHK2 and G2 check point abrogation, respectively. | ||
| M10498 | CCG-222740 | Ras |
| CCG-222740 is a selective, orally active Rho/myocardin-related transcription factor (MRTF) pathway inhibitor. | ||
| M10963 | ARCC-4 | Others |
| ARCC-4 is based on PROTAC technology, a nanomolar grade androgen receptor (AR) degrader D50 The value is 5 nM. ARCC-4 is an AR PROTAC recruited by von Hippel-Lindau (VHL) based on enzalutamide. ARCC-4 effectively degrades AR mutations associated with antiandrogen studies. | ||
| M11295 | Mezigdomide (CC-92480) | E1/E2/E3 Enzyme |
| Mezigdomide (CC-92480) is a novel protein reducing agent and cereblon E3 ligase modulator (CELMoD). Mezigdomide has a strong affinity with Cereblon and has anti-myeloma activity. | ||
| M11516 | Vimseltinib | CSF-1R (c-Fms) |
| DCC-3014 | ||
| Vimseltinib (DCC-3014) is a highly selective, orally active inhibitor of colony-stimulating factor-1 receptor (CSF-IR) and c-Kit with IC50 values of <0.01 μM and 0.1-1 μM, respectively.Vimseltinib is used in studies related to tenosynovial giant cell tumors (TGCT). | ||
| M13620 | CCT244747 | Checkpoint |
| CCT244747 is a potent, orally bioavailable and highly selective CHK1 inhibitor, with an IC50 of 7.7 nM; CCT244747 also abrogates G2 checkpoint with an IC50 of 29 nM. | ||
| M13928 | CCR2 antagonist 4 | CCR |
| Teijin compound 1 | ||
| CCR2 antagonist 4 (Teijin compound 1) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM. | ||
| M15016 | Recombinant Human Eotaxin-2/CCL24 (E. coli) | Cytokines and Growth Factors |
| C-C motif chemokine 24; CK-beta-6 | ||
| Recombinant human Eotaxin-2/CCL24 protein (E. coli) is a new CC chemokine recently discovered. It is produced by activated monocytes and T lymphocytes. Protein structure: CCL24 (VAL27-ALA104), Accession # : O00175. | ||
| M15026 | Recombinant Human MIP-1β /CCL4 (E. coli) | Cytokines and Growth Factors |
| MIP-1 beta; Macrophage Inflammatory Protein-1β; CCL-4; ACT-2 | ||
| Macrophage inflammatory protein 1β (MIP-1β), also known as Chemokine (C-motif) ligand 4 (CCL4), is a small cytokine in the CC Chemokine family. It is a chemical attractant for natural killer cells, monocytes and a variety of other immune cells. Protein structure: MIP-1β (ALA24-ASN92), Accession # P13236-1. | ||
| M14077 | Recombinant Human MIP-3α/CCL20 (CHO) | Cytokines and Growth Factors |
| CCL-20; CKb4; Exodus; LARC | ||
| Macrophage Inflammatory Protein-3 (MIP-3α), also known as chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC), is a small cytokine belonging to the CC chemokine family. | ||
| M14156 | CC-401 hydrochloride | JNK |
| CC401 HCl | ||
| CC-401 hydrochloride is a potent inhibitor of all three forms of JNK with Ki of 25 to 50 nM. | ||
| M14825 | Sincalide ammonium | Peptides |
| Cholecystokinin octapeptide ammonium; CCK-8 ammonium; SQ19844 ammonium | ||
| Sincalide ammonium (Cholecystokinin octapeptide ammonium) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. | ||
| M19980 | Recombinant Mouse MIP-3α/CCL20 (E. coli) | Cytokines and Growth Factors |
| CCL-20; CKb4; Exodus; LARC; MIP-3-alpha | ||
| Macrophage Inflammatory Protein-3 (MIP-3α), also known as chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC), is a small cytokine belonging to the CC chemokine family. Determined by a chemotaxis bioassay using human CCR6 transfected murine BaF3 cells, the biologically active is in a concentration range of 0.1-10.0 ng/ml. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
