About 30 results found for searched term "5-PT" (0.029 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2226 | Melatonin | Melatonin Receptor |
| Melatonex; N-Acetyl-5-methoxytryptamine; MT | ||
| Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation. | ||
| M2588 | TGR5 Receptor Agonist | GPCR19/TGR5 |
| TGR5 Receptor Agonist is a potent TGR5(GPCR19) agonist which showed improved potency in the U2-OS cell assay (pEC50 = 6.8) and in melanophore cells (pEC50 = 7.5). | ||
| M3004 | Serotonin hydrochloride | 5-HT Receptor |
| 5-Hydroxytryptamine hydrochloride; 5-HT hydrochloride | ||
| Serotonin hydrochloride is a monoamine neurotransmitter and Endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM. | ||
| M4972 | 3-Amino-5-mercapto-1,2,4-triazole | Plant growth regulators |
| Amitrole (3-amino-1,2,4-triazole) is a widely used herbicide. | ||
| M9071 | Amyloid beta-peptide(25-35) | Amyloid |
| Aβ25-35; β-Amyloid peptide(25-35) | ||
| Amyloid beta-peptide(25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, has shown neurotoxic activities in cultured cells. | ||
| M10329 | Ningetinib | VEGFR/PDGFR |
| CT-053; DE-120; CT053PTSA | ||
| Ningetinib is a potent, orally bioavailable tyrosine kinase inhibitor for Axl, VEGFR2 and c-Met with IC50 values of <1.0, 1.9 and 6.7 nM, respectively. | ||
| M13360 | Serotonin | 5-HT Receptor |
| 5-Hydroxytryptamine; 5-HT | ||
| Serotonin is a monoamine neurotransmitter and endogenous 5-HT receptor agonist in CNS. Serotonin is also an inhibitor of catechin-o-methyltransferase (COMT) with a Ki value of 44 μM. Serotonin is also a natural product of animals. | ||
| M14310 | Bergamottin | Cytochrome P450 (e.g. CYP17) |
| 5-Geranoxypsoralen; Bergamotine; Bergaptin | ||
| Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM. | ||
| M14379 | L-5-Hydroxytryptophan | Metabolite/Endogenous Metabolite |
| L-5-HTP; Oxitriptan | ||
| L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist. | ||
| M14392 | N-Acetyl-5-hydroxytryptamine | Metabolite/Endogenous Metabolite |
| N-Acetylserotonin; Normelatonin; O-Demethylmelatonin | ||
| N-Acetyl-5-hydroxytryptamine is a Melatonin precursor, and that it can potently activate TrkB receptor. | ||
| M14402 | Pimelic acid | Metabolite/Endogenous Metabolite |
| Heptanedioic acid; 1,5-Pentanedicarboxylic acid; 1,7-Heptanedioic acid | ||
| Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine. | ||
| M16030 | 5-Hydroxytryptophan | Alkaloids |
| 5-Hydroxytryptophan | ||
| M16571 | 3,5,6,7,3',4',5'-Heptamethoxyflavone | Flavonoids |
| 3,5,6,7,3',4',5'-Heptamethoxyflavone | ||
| M16572 | 3,5,7,8,3',4',5'-Heptamethoxyflavone | Flavonoids |
| 3,5,7,8,3',4',5'-Heptamethoxyflavone | ||
| M17044 | (3R,5R)-1-(4-Hydroxyphenyl) -7-phenylheptane-3,5-diol | Phenols |
| (3R,5R)-1-(4-Hydroxyphenyl) -7-phenylheptane-3,5-diol | ||
| M17047 | (4Z,6E)-5-Hydroxy-1,7- diphenylhepta-4,6-dien-3-one | Phenols |
| (4Z,6E)-5-Hydroxy-1,7- diphenylhepta-4,6-dien-3-one | ||
| M17061 | (Z)-5-Hydroxy-1,7-diphenylhept-4-en-3-one | Phenols |
| (Z)-5-Hydroxy-1,7-diphenylhept-4-en-3-one | ||
| M17062 | (3S,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol | Phenols |
| (3S,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol | ||
| M17070 | (R)-5-Hydroxy-1,7-diphenylheptan-3-one | Phenols |
| (R)-5-Hydroxy-1,7-diphenylheptan-3-one | ||
| M17071 | 5-Hydroxy-1,7-diphenyl-6-hepten-3-one | Phenols |
| 5-Hydroxy-1,7-diphenyl-6-hepten-3-one | ||
| M17158 | 5-Heptadecylresorcinol | Phenols |
| 5-Heptadecylresorcinol | ||
| M17310 | 1,5-Epoxy-3-hydroxy-1-(3,4-dihydroxy-5-methoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane | Phenols |
| 1,5-Epoxy-3-hydroxy-1-(3,4-dihydroxy-5-methoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane | ||
| M17928 | (1β,2β,3β,4β,5β,7α,22α)-27-(β-D-Glucopyranosyloxy)-1,2,3,4,5,7,22-heptahydroxyfurost-25-en-6-one | Others |
| （1β,2β,3β,4β,5β,7α,22α）-27-（β-D-Glucopyranosyloxy）-1,2,3,4,5,7,22-heptahydroxyfurost-25-en-6-one | ||
| M18052 | 3,5,6,7,8,3',4'-Heptamethoxyflavone | Others |
| 3,5,6,7,8,3',4'-Heptamethoxyflavone | ||
| M21448 | Recombinant Mouse IL-15RA (HEK293, C-Fc) | Cytokines and Growth Factors |
| Interleukin-15 receptor subunit alpha | ||
| Recombinant mouse interleukin-15 receptor subunit α is produced by mammalian expression systems, and the target gene encoding Gly33-Lys205 is expressed with Fc tag at the C-terminal. Protein number: Q60819. | ||
| M24634 | Luspatercept | TGF-beta/Smad |
| ACE-536; luspatercept-aamt | ||
| Luspatercept (ACE-536) is a first-in-class recombinant modified ActRIIB fusion protein that binds with transforming growth factor β superfamily ligands. Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors. Luspatercept binds with GDF11 and inhibits Smad2/3 signaling. Luspatercept can be used for the research of anemia. | ||
| M29687 | 5-Bromo-L-tryptophan | Metabolite/Endogenous Metabolite |
| 5-Bromo-L-tryptophan is an α-amino acid derivative that can be found in Semenospongia sp.. | ||
| M29781 | 5-C-heptyl-DNJ | Others |
| 5-heptyl-DNJ is a potent GAA agonist with a Ki of 0.0047 μM. 5-C-heptyl-DNJ increases GAA activities by chaperrone effects. | ||
| M29977 | Pemetrexed disodium heptahydrate | Antifolate |
| LY231514 disodium heptahydrate | ||
| Pemetrexed disodium heptahydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively. | ||
| M30571 | 5-Carboxamidotryptamine | 5-HT Receptor |
| 5-CT | ||
| 5-Carboxamidotryptamine (5-CT) is a 5-HT1A, 5-HT1B, 5-HT1D, 5-HT5A, 5-HT7 receptor agonist. 5-Carboxamidotryptamine has a Ki value of 4.6 nM for cloned human 5-HT5A receptor. 5-Carboxamidotryptamine causes a dose-dependent reduction in rectal temperature of mice. | ||
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