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Luspatercept (ACE-536) is a first-in-class recombinant modified ActRIIB fusion protein that binds with transforming growth factor β superfamily ligands. Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors. Luspatercept binds with GDF11 and inhibits Smad2/3 signaling. Luspatercept can be used for the research of anemia.
| CAS Number | 1373715-00-4 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[1] No authors listed. Luspatercept
[2] No authors listed. Luspatercept
[3] Maria Domenica Cappellini, et al. Blood Adv. The use of luspatercept for thalassemia in adults
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Products are for research use only. Not for human use. We do not sell to patients.
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