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L-5-Hydroxytryptophan

Cat. No. M14379

All AbMole products are for research use only, cannot be used for human consumption.

L-5-Hydroxytryptophan Structure
Synonym:

L-5-HTP; Oxitriptan

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Quality Control & Documentation
Biological Activity

L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia.

Chemical Information
Molecular Weight 220.22
Formula C11H12N2O3
CAS Number 4350-09-8
Solubility (25°C) DMSO 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jing Huang, et al. L-5-hydroxytryptophan promotes antitumor immunity by inhibiting PD-L1 inducible expression

[2] Lisheng Xu, et al. Directed Evolution Improves the Enzymatic Synthesis of L-5-Hydroxytryptophan by an Engineered Tryptophan Synthase

[3] Massimo E Maffei. 5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology

[4] M Irwin, et al. L-5-Hydroxytryptophan-induced delirium

[5] H M van Praag, et al. L-5-hydroxytryptophan in depression and anxiety

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Keywords: L-5-Hydroxytryptophan, L-5-HTP; Oxitriptan supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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