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Trigonelline chloride is an alkaloid with potential antidiabetic activity that can be isolated from Trigonella foenum-graecum L or Leonurus artemisia. Trigonelline chloride is a potent Nrf2 inhibitor that blocks Nrf2-dependent proteasome activity, thereby enhancing apoptosis in pancreatic cancer cells. Trigonelline chloride also has anti-HSV-1, antibacterial, and antifungal activity, and induces ferroptosis.
| Molecular Weight | 173.6 |
| Formula | C7H8ClNO2 |
| CAS Number | 6138-41-6 |
| Form | Solid |
| Solubility (25°C) | Water 50 mg/mL DMSO 10 mg/mL |
| Storage | 4°C, dry, sealed |
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