Certificate of Analysis
| Product Name: | Trigonelline hydrochloride |
| Catalog Number: | M4551 |
| CAS Number: | 6138-41-6 |
Physical and Chemical Properties
| Formula: | C7H8ClNO2 |
| Molecular Weight: | 173.6 |
| Form: | Solid |
| Solubility: | Water 50 mg/mL; DMSO 10 mg/mL |
| Storage: | 4°C, dry, sealed |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Trigonelline chloride is an alkaloid with potential antidiabetic activity that can be isolated from Trigonella foenum-graecum L or Leonurus artemisia. Trigonelline chloride is a potent Nrf2 inhibitor that blocks Nrf2-dependent proteasome activity, thereby enhancing apoptosis in pancreatic cancer cells. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |