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SPI-112

Cat. No. M10739

All AbMole products are for research use only, cannot be used for human consumption.

SPI-112  Structure
Size Price Availability Quantity
10mg USD 50  USD50 In stock
25mg USD 105  USD105 In stock
50mg USD 190  USD190 In stock
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Quality Control & Documentation
Biological Activity

SPI-112 is a potent, selective and competitive SHP2 (PTPN11) inhibitor of SHP2, protein tyrosine phosphatase (PTP) and PTP1B IC50 1 μM, 18.3 μM, and 14.5 μM, respectively.

Chemical Information
Molecular Weight 468.46
Formula C22H17FN4O5S
CAS Number 1051387-90-6
Solubility (25°C) DMSO ≥ 40 mg/mL
Storage 4°C, protect from light, dry
References

[1] Liwei Chen, et al. Biochem Pharmacol. Inhibition of cellular Shp2 activity by a methyl ester analog of SPI-112

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  Catalog
Abmole Inhibitor Catalog




Keywords: SPI-112 supplier, Phosphatase, inhibitors, activators

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