Certificate of Analysis
| Product Name: | SPI-112 |
| Catalog Number: | M10739 |
| CAS Number: | 1051387-90-6 |
Physical and Chemical Properties
| Formula: | C22H17FN4O5S |
| Molecular Weight: | 468.46 |
| Solubility: | DMSO ≥ 40 mg/mL |
| Storage: | 4°C, protect from light, dry |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | SPI-112 is a potent, selective and competitive SHP2 (PTPN11) inhibitor of SHP2, protein tyrosine phosphatase (PTP) and PTP1B IC50 1 μM, 18.3 μM, and 14.5 μM, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |