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Silibinin, the main flavonoid extracted from the milk thistle Silybum marianum, displays hepatoprotective properties in acute and chronic liver injury. Silibinin is an effective SARS-CoV-2 main protease (Mpro) inhibitor. Silibinin can significantly reduce tumor cell proliferation, angiogenesis as well as insulin resistance.
J Adv Res. 2022 May 13;S2090-1232(22)00117-5.
Combination of natural polyphenols with a precursor of NAD+ and a TLR2/6 ligand lipopeptide protects mice against lethal γ radiation
Silibinin purchased from AbMole
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Animal models | Athymic (nu/nu) male nude mice s.c. injected with 6 × 106 DU145 cells |
Formulation | 0.5% CMC (w/v) in saline |
Dosages | 200 mg/kg |
Administration | oral gavage just before the first dose of IR and continued for 5 days/week |
Molecular Weight | 482.44 |
Formula | C25H22O10 |
CAS Number | 22888-70-6 |
Solubility (25°C) | DMSO 96 mg/mL |
Storage | Powder -20°C |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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