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Ivermectin (MK-933)

Cat. No. M2256

All AbMole products are for research use only, cannot be used for human consumption.

Ivermectin (MK-933) Structure
Synonym:

Stromectol; MK-933; CD-5024; K-237

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
10mM*1mL in DMSO USD 40  USD40 In stock
100mg USD 24  USD24 In stock
500mg USD 48  USD48 In stock
1g USD 80  USD80 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Ivermectin (MK-933) is an importin α5 inhibitor. Ivermectin (MK-933) is a broad-spectrum antiparasitic medication. Ivermectin also modulates glutamate- and GABA-activated chloride channels. Ivermectin potentiates glycine-gated currents at low concentrations (30 nM).

Chemical Information
Molecular Weight 875.09
Formula C48H74O14
CAS Number 70288-86-7
Solubility (25°C) DMSO 70 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yiwei Xiong, et al. Cell Mol Immunol . ADAP restraint of STAT1 signaling regulates macrophage phagocytosis in immune thrombocytopenia

[2] Fabio Rocha Formiga, et al. Ivermectin: an award-winning drug with expected antiviral activity against COVID-19

[3] Fatemeh Heidary, et al. Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen

[4] Arnzazu Gonzlez Canga, et al. The pharmacokinetics and interactions of ivermectin in humans--a mini-review

[5] Cynthia A Guzzo, et al. Safety, tolerability, and pharmacokinetics of escalating high doses of ivermectin in healthy adult subjects

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Keywords: Ivermectin (MK-933), Stromectol; MK-933; CD-5024; K-237 supplier, Autophagy, inhibitors, activators

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