| Cat.No. | Name | Information |
|---|---|---|
| M1658 | Axitinib | Axitinib (AG013736) inhibits multiple targets including VEGFR, PDGFR and cKit. |
| M2194 | SU5402 | SU5402 is a potent and selective VEGFR and FGFR inhibitor with IC50 values of 0.02, 0.03, 0.51 and > 100 μM for VEGFR2, FGFR1, PDGFRβ and EGFR respectively. |
| M1838 | Masitinib | Masitinib is a tyrosine kinase inhibitor targeting stem cell factor receptor (c-kit) and platelet-derived growth factor (PDGF) receptor. |
| M1956 | Apatinib mesylate | Apatinib is a small-molecule multitargeted tyrosine kinase inhibitor of VEGFR2 with an IC50 of 2.43 nM. |
| M1841 | Lenvatinib | Lenvatinib (E7080) is a potent inhibitor of multiple tyrosine kinases, including VEGF-R3 tyrosine kinase (IC50=5.2 nM) and VEGF-R2 tyrosine kinase (IC50=4.0 nM). |
| M1669 | Regorafenib | Regorafenib (BAY 73-4506) is a novel oral multikinase inhibitor of c-KIT, VEGFR2, B-Raf with IC50s of 17, 40 and 69 nM respectively. |
| M1827 | Sorafenib Tosylate | Sorafenib (BAY 43-9006) Tosylate is an orally active multikinase inhibitor of tyrosine protein kinases VEGFR/PDGFR and RAF/MEK/ERK with IC50 values of 6, 22, 38 nM for Raf-1, wt BRAF and V599E mutant BRAF. |
| M1964 | Vandetanib | Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase (IC50=40 nM). Vandetanib also inhibited VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM). |
| M5005 | Regorafenib Monohydrate | Regorafenib is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively. |
| M1882 | Vatalanib dihydrochloride | Vatalanib is a selective small molecule protein kinase inhibitor of VEGF receptors 1-3 with IC50 of 37 nM. |
| M58124 | Conbercept | Conbercept (KH902) is a monoclonal antibody targeting VEGFRA fused to the IGHG1 Fc fragment. Conbercept is produced by the fusion of the second C-LIKE of FLT1 and the third and fourth C-LIKE of KDR with IGHG1 Fc. |
| M57224 | SU5208 | SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2). |
| M57223 | VEGFR-IN-1 | VEGFR-IN-1 is a potent angiogenesis inhibitor with IC50s of 0.02, 0.18, 0.24 7.3, and 7 µM for KDR, Flt-1, c-Kit, EGF-R, and c-Src, respectively. |
| M57222 | (Z)-Orantinib | (Z)-Orantinib ((Z)-SU6668) is a potent, selective, orally active and ATP competitive inhibitor of Flk‐1/KDR, PDGFRβ, and FGFR1, with IC50s of 2.1, 0.008, and 1.2 µM, respectively. |
| M57221 | (Rac)-SAR131675 | (Rac)-SAR131675 is the racemate of SAR131675. |
| M57209 | AGL 2043 | AGL 2043 is an effective inhibitor of PDGFR (IC50=0.8 μM) and TEL-PDGFR kinases, as well as FLT3 and KIT kinases. |
| M57208 | PDGFR Tyrosine Kinase Inhibitor III | PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III), a multikinase inhibitor, inhibits PDGFR, EGFR, FGFR, PKA, and PKC, respectively. |
| M54213 | Oglufanide | Oglufanide (H-Glu-Trp-OH) is a dipeptide immunomodulator isolated from calf thymus. |
| M50404 | KLTWQELYQLKYKGI | KLTWQELYQLKYKGI (QK) is a VEGF mimicking peptide, binds to the VEGF receptors and competes with VEGF. |
| M50403 | Protein LMWP | Protein LMWP is a cell-penetrating peptide with vascular endothelial growth factor (VEGF) inhibitory activity. |
| M50402 | CBO-P11 | CBO-P11 specifically binds to receptor of VEGFR-2 and is used as targeting ligand for tumor angiogenesis. |
| M49921 | Aiphanol | Aiphanol is an extract of Poria cocos that directly targets and inhibits VEGFR2 and COX2, thereby blocking angiogenesis and tumor growth. |
| M43553 | VEGFR2-IN-3 | VEGFR2-IN-3 is a potent VEGFR2 inhibitor. |
| M43552 | FGFR1/VEGFR2-IN-1 | FGFR1/VEGFR2-IN-1 is an FGFR1/VEGFR2 inhibitor. |
| M43551 | VEGFR-2-IN-33 | VEGFR-2-IN-33 is a VEGFR inhibitor (IC50: 61.04 nM). |
| M43550 | JNJ 17029259 | JNJ 17029259 is an orally active and selective VEGF-R2 kinase inhibitor. |
| M43549 | VEGFR-2-IN-32 | VEGFR-2-IN-32 is an inhibitor of VEGFR-2 with an IC50 of 8.93 nM. |
| M43548 | VEGFR2-IN-4 | VEGFR2-IN-4 is a potent and selective VEGFR2 kinase inhibitor, with a GI50 of 0.7 nM. |
| M43547 | VEGFR-2-IN-31 | VEGFR-2-IN-31 is a potent VEGFR-2 inhibitor (IC50=8.93 nM), and an anti-prostate cancer agent. |
| M43546 | Bevasiranib | Bevasiranib is a siRNA designed to silence the genes that produce vascular endothelial growth factor (VEGF). |
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