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ROS Reactive Oxygen Species

Cat.No.  Name Information
M5385 Acetylcysteine (NAC) Acetylcysteine (NAC; N-acetyl-l-cysteine) is a ROS inhibitor that antagonizes the activity of several proteasome inhibitors. It is also an inhibitor of the tumor necrosis factor TNF.
M6685 DMPO DMPO is a nitric oxide spin trap; measure oxygen-centered free radicals.
M4944 BAPTA BAPTA is a calcium-specific aminopolycarboxylic acid.
M21349 Phycocyanobilin Phycocyanobilin is an effective scavenger for various reactive oxygen species. Phycocyanobilin can be used for the research of Alzheimer’s disease.
M30254 5-Galloylquinic acid 5-Galloylquinic acid, an main scavenger of the reactive oxygen species (ROS) in green tea.
M29130 2′,7′-Dichlorofluorescein diacetate 2′,7′-Dichlorofluorescein diacetate (DCFH2-DA) is a cell-permeable fluorescent probe. 2′,7′-Dichlorofluorescein diacetate can be used to detect the generation of reactive oxygen intermediates and for assessing the overall oxidative stress in toxicological phenomenon.
M25560 HG106 HG106 is a potent SLC7A11 inhibitor, it can enhance ROS generation, ER stress, and lead to ultimately growth arrest specifically in KRAS-mutant lung adenocarcinoma (LUAD).
M25482 Capillarisin Capillarisin, as a constituent from Artemisiae Capillaris herba, is found to exert anti-inflammatory and antioxidant properties.
M21415 Trabectedin Trabectedin (Ecteinascidin 743; ET-743) is a tetrahydroisoquinoline alkaloid that binds to the minor groove of DNA, blocks stress-induced transcription of proteins, induces DNA backbone cleavage and apoptosis, and increases ROS production in MCF-7 and MDA-MB-453 cells. Trabectedin can be used in soft tissue sarcoma and ovarian cancer studies.
M20721 Raspberry ketone glucoside Raspberry ketone glucoside (RKG), a natural product in raspberry fruit, is an antioxidant that has the inhibitory effect on the melanin synthesis.
M19982 CYPMPO CYPMPO is a solvent used for electron spin resonance (ESR) radical spin capture. CYPMPO is a circular DEPMPO type nitrone used to evaluate the spin trapping ability of hydroxyl and superoxide radicals. Antioxidant and antitumor activity.
M18997 Pelargonidin chloride Pelargonidin chloride is an anthocyanidin and also is a scavenger of nitric oxide radical and has antioxidant activities. Pelargonidin inhibits cell viability and induces cell cycle arrest at sub-G1 phase. Pelargonidin chloride increases the mRNA and protein expression of HO-1, NQO1, Nrf2.
M18503 Salvianolic acid Y Salvianolic acid Y is a phenolic acid which can rescue cell injury by H2O2.
M18277 N-trans-Caffeoyltyramine N-trans-Caffeoyltyramine is an effective inflammatory response regulator, which has antioxidant activity and anticoagulation effects.
M17335 Moracin O Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production.
M15088 Clovamide Clovamide is a natural phenolic compound with anti-inflammatory and neuroprotective effects, a potent antioxidant, and an excellent ROS and oxygen free radical scavenger.
M15075 Ensulizole Ensulizole (PBSA) is a water-soluble sunscreen, a sulfonated UV absorber characterized by strong absorption of UVB and partial absorption of UVA. Ensulizole can damage DNA by producing reactive oxygen species (ROS) when exposed to ultraviolet or sunlight.
M14783 Temoporfin Temoporfin (m-THPC), a reduced porphyrin, is a potent second-generation photosensitizer. Temoporfin can be used in the research of photodynamic therapy (PDT) for head and neck cancers.
M14116 Reynoutrin Reynoutrin (Quercetin-3-D-xyloside) is a flavonoid from Psidium cattleianum, with antioxidant and radical-scavenging activity.
M14111 Glucoraphanin Glucoraphanin, a natural glucosinolate found in cruciferous vegetable, is a stable precursor of the Nrf2 inducer sulforaphane, which possesses antioxidant, anti-inflammatory, and anti-carcinogenic effects.
M14109 DMNQ DMNQ is a redox cycling agent that generates both superoxide and hydrogen peroxide intracellularly in a concentration dependent manner. DMNQ increases ROS generation.
M14107 D-α-Hydroxyglutaric acid disodium D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria.
M11302 Pyropheophorbide-a Pyropheophorbide- A (Ppa) is a photosensitizer used in tumor photodynamic therapy (PDT).
M11203 Cinnamtannin B-1 Cinnamtannin B-1 is a proanthocyanidin that has a variety of biological functions, including antioxidant effects. Cinnamtannin B-1 inhibits RANKL-induced osteoclasty and prevents osteoporosis induced by ovarian resection. Cinnamtannin B-1 inhibition can be used for the study of osteoporosis and colon cancer.




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