DMPO is a water soluble nitric oxide spin trap; allows the measurement of oxygen-centered free radicals in biological systems at room temperature using electron spin resonance (ESR). Has a high reaction rate constant for superoxide and hydroxyl radicals, and distinguishes simultaneously among a variety of important biologically generated free radicals.
Journal of Materials Chemistry B. 2023 Mar 29.
TME-triggered copper-coordinated engineered programmable nanogenerator for on-demand cascade-amplifying oxidative stress
DMPO purchased from AbMole
Applied Surface Science. .
Manganese oxide on activated carbon with peroxymonosulfate activation for enhanced ciprofloxacin degradation: Activation mechanism and degradation pathway
DMPO purchased from AbMole
| Molecular Weight | 113.16 |
| Formula | C6H11NO |
| CAS Number | 3317-61-1 |
| Solubility (25°C) | Water 100 mg/mL DMSO 90 mg/mL |
| Storage | -20°C, protect from light, dry, sealed |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
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| Arg-Tyr
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