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L-Ascorbyl 6-palmitate is a synthetic lipophilic ascorbic acid derivative. L-Ascorbyl 6-palmitate is an effective preservative in foods and an effective dietary antitumor promoter in mice. Studies indicate that dietary AP is a source of tissue vitamin C in animals. Besides, dietary L-Ascorbyl 6-palmitate possesses weak antiscorbutic activity in guinea pigs and enhances vitamin C nutriture in humans. In a study, daily mean weight loss during repletion in control animals receiving placebo was significantly greater than that for both L-ascorbic acid (AA) and L-Ascorbyl 6-palmitate animals for days 3–10 of repletion. Daily mean weight loss for AP animals was significantly greater than that for AA animals on days 5 and 6 of repletion. By comparing areas of the weight-time curve during repletion, L-Ascorbyl 6-palmitate appeared to be about 50% as effective as AA in reversing scurvy.
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Preparation method | |
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Animal models | Male MF1 mice |
Formulation | |
Dosages | 1412 mg/kg |
Administration | Orally |
Molecular Weight | 414.53 |
Formula | C22H38O7 |
CAS Number | 137-66-6 |
Form | Solid |
Solubility (25°C) | DMSO 80 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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