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Capillarisin, as a constituent from Artemisiae Capillaris herba, is found to exert anti-inflammatory and antioxidant properties. Capillarisin antagonizes bupivacaine-induced oxidative stress via activating the PI3K/PKB pathway in SH-SY5Y cells. Capillarisin inhibits bupivacaine-induced mitochondrial injury and endoplasmic reticulum stress via activating PI3K/PKB pathway. Capillarisin (20 and 80 mg/kg; i.p.; 1 hour) pretreatment strongly inhibits NF-κB mediated genes (iNOS, COX-2) in ICR mice.
| Molecular Weight | 316.26 |
| Formula | C16H12O7 |
| CAS Number | 56365-38-9 |
| Solubility (25°C) | DMSO >10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related ROS Products |
|---|
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N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H2S) and can be used as an H2S producer. |
| Manganese(salen) chloride
Manganese(salen) chloride (EUK-8) is a superoxide dismutase and catalase mimetic, it is an antioxidant with oxyradical scavenging properties. |
| Magnoloside F
Magnoloside F is a natural compound that can be isolated from the Magnolia officinalis, and has antioxidant activity. |
| Porphyra 334
Porphyra 334 is an antioxidative and anti-photoaging agent. |
| Photosensitizer-1
Photosensitizer-1 is a photosensitizer. |
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